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Copyright © All Samadhan - Operated by M/S. Genius Experts | All Rights Reserved
DBID
Registration ID: 176322642
Trade License: TRAD/DNCC/040904/2023
Copyright © All Samadhan - Operated by M/S. Genius Experts | All Rights Reserved
DBID
Registration ID: 176322642
Trade License: TRAD/DNCC/040904/2023
Popular Pharmaceuticals Ltd. · Tablet
/ 8 tablets kit
The information provided on All Samadhan is intended for general informational purposes only and is prepared based on our best practices. It is not a substitute for professional medical advice, diagnosis, or treatment. While we strive to keep the information accurate and up to date, we do not guarantee its completeness or accuracy. The absence of specific information or warnings about any medicine or service should not be considered as an assurance or endorsement by All Samadhan. All Samadhan shall not be held responsible for any consequences arising from the use of this information. We strongly recommend consulting a qualified healthcare professional or physician for any medical concerns, questions, or clarifications.
This combination is indicated for the treatment of H. pylori infection in adults.
14 days daily administration for morning, mid-day and night dowing each containing the following two drug products:
Tablet: Vonoprazan 20 mg
Capsule: Amoxicillin 500 mg
The recommended dosage regimen is
Morning: 1 Vonoprazan 20 mg tablet & 2 Amoxicillin 500 mg capsules
Midday: 2 Amoxicillin 500 mg capsules
Night: 1 Vonoprazan 20 mg tablet & 2 Amoxicillin 500 mg capsules with or without food, for 14 days
Drug-drug interaction may occur with strong or moderate CYP3A inducers. Probenecid, Itraconazole, Allopurinol, Omeprazole, Saquinavir, Ritonavir, Etravirine & Rilpivirine.
Most common adverse reactions (22%) were diarrhea, abdominal pain, vulvovaginal candidiasis and nasopharyngitis.
Based on findings from animal studies and observational studies in pregnant women with use of Clarithromycin, use of Vonomax Duo is not recommended in pregnant women. Avoid breastfeeding during Voromax Duo therapy.
Hypersensitivity Reactions: Serious and occasionally fatal reactions (e.g., anaphylaxis) have been reported with components of Vonomax Duo. If hypersensitivity reactions occur, discontinue Vonomax Duo and institute immediate therapy (eg, anaphylaxis management).Severe Cutaneous Adverse Reactions (SCAR): Discontinue Vonomax Duo at the first signs or symptoms of SCAR or other signs of Hypersensitivity and consider further evaluation.Clostridioides difficile-associated diarrhea (CDAD): Evaluate if diarrhea occurs with Vonomax Duo.
Pediatric Use: Safety and effectiveness of Vornomax Duo in Pediatric patients have not been establishedRenal Impairment: No dosage adjustment of Vonomer Duo is recommended in patients with mild to moderate renat impelment (eGFR 30 to 89 mL/min). Avoid the use of Vonomax Duo in patients with severe renal impairment (eGFR <30 mL/min)Hepatic Impairment: No dosage adjustment of Vonomer Duo is recommended in patients with mild hepatic impairment (Child-Pugh A). Avoid the use of Vonomax Duo in patients with moderate to severe hepatic impairment (Child-Pugh B or C).
Store at below 30°C in a dry place protected from light. Keep out of reach of children.