What Is Unipem 200 mg Indications and Uses?

Unipem 200 mg (Faropenem) tablet is indicated in the treatment of the following infections: Lower respiratory tract infections : acute bronchitis, pneumonia, pulmonary suppuration. Ear, nose, and throat (ENT) infections : otitis externa, tympanitis, sinusitis. ... Read more Unipem 200 mg (Faropenem) tablet is indicated in the treatment of the following infections: Lower respiratory tract infections : acute bronchitis, pneumonia, pulmonary suppuration. Ear, nose, and throat (ENT) infections : otitis externa, tympanitis, sinusitis. Genito-urinary infections : pyelonephritis, cystitis, prostatitis, seminal gland inflammation. Upper respiratory tract infections : pharyngitis, tonsillitis. Skin and skin structure infections : pustular acne, folliculitis, contagious impetigo, erysipelas, lymphangitis, suppurative nail inflammation, subcutaneous abscess, hidradenitis (sweat gland inflammation), infective sebaceous cyst, chronic pyoderma, secondary infection of external wounds or surgical wounds. Gynecological infections : adnexitis, bartholin gland inflammation.

Pharmacology (Source, Chemical and Physical Composition) Of Unipem 200 mg

Unipem 200 mg (Faropenem) is a penem class of antimicrobial and has bactericidal activity against a variety of gm-ve, gm+ve and anaerobic bacteria. Faropenem is bactericidal, with a strong affinity for the high molecular penicillin binding proteins (PBPs) of the cell wall, which is essential for the multiplication of bacilli; it, thus, acts by inhibiting the cell wall synthesis. Faropenem shows broad antibacterial activity against both aerobic and anaerobic Gram-positive and Gram-negative bacteria. Faropenem is highly stable against various beta lactamases and binds preferentially to the PBPs, 2 and 1A, of Escherichia coli (E. coli).

Dosage And Administration of Unipem 200 mg

Upper respiratory tract infections : 150 mg t.i.d., can be increased to 200 mg t.i.d. ENT infections : 200 mg t.i.d., can be increased to 300 mg t.i.d. Lower respiratory tract infections : 200 mg t.i.d., can be increased to 300 mg t.i.d. Skin and skin structure infections : 150 mg t.i.d., can be increased to 200 mg t.i.d. Genito-urinary infections : 200 mg t.i.d., can be increased to 300 mg t.i.d. Gynecological infections : 150 mg t.i.d., can be increased to 200 mg t.i.d.

Drug Interactions of Unipem 200 mg

Imipenem and Cilastatin sodium combination : It has been reported that in animal studies (rat), the concentration of Unipem 200 mg (Faropenem) in the blood increases. It is due to the obstruction of metabolic fermentation by cilastatin. Furosemide : It has been reported in animal studies (dog), that the kidney toxicity of Unipem increases. Sodium valproate : It has been reported that due to joint usage with carbapenem drugs (meropenem, panipenem and imipenem-cilastatin sodium) the concentration of valproic acid in the blood reduces, and there is a recurrence of epileptic fits.

Side Effects of Unipem 200 mg

Common side effects of Unipem 200 mg (Faropenem) are Headache, Nausea, Vomiting, Stomach pain and Diarrhea.

Precautions And Warnings for Unipem 200 mg

Unipem 200 mg (Faropenem) should be administered with caution in the following: Patients with a past history of hypersensitivity to penicillin, cephem or carbapenem drugs. Patients with a family history of atopy. Patients with renal impairment. The dosage should be reduced or the interval between doses should be increased. Geriatric patients. Patients with poor oral intake or poor general state (since there are cases that show symptoms of vitamin K deficiency, proper monitoring should be done).

Use During Pregnancy and Lactation

Safety regarding therapy during pregnancy has not been established. In pregnant women or expectant mothers, the medicine should be given only if the benefit of the treatment is greater than the risks involved. Unipem 200 mg (Faropenem) is excreted in human milk. Therefore, Faropenem should be given to nursing mothers only if the benefits outweigh the risks.

Storage Conditions of It

Store Unipem at room temperature between 20°C to 25°C in its original package. Safely throw away any Unipem that is out of date or no longer needed. Keep Unipem and all medicines out of the reach of children. Protect from moisture. Pack Image: Unipem 200 mg Tablet Thanks for using MedEx! How would you rate your experience so far?