OTC

Tritin 100 mg

Renata PLC · Tablet

GenericTrimebutine Maleate

Strength100 mg

Total Strip3

Strip Size10

Unit Price

৳ 5

/ Piece

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Medicine Description

INDICATIONS

Trimebutine Maleate is indicated for-

Treatment and relief of symptoms associated with Irritable Bowel Syndrome (IBS).
Postoperative paralytic ileus in order to accelerate the resumption of the intestinal transit following abdominal surgery.

PHARMACOLOGY

Trimebutine Maleate is a noncompetitive spasmolytic agent.lt possesses moderate opiate receptor affinity and has marked anti-serotonin activity especially on 'mu' receptors. It induces regulation of spontaneous activity and increases synchronization between electrophysiological spikes and contractions in isolated guinea pig strips of colon and ileum. However, it does not alter normal motility, but regulates abnormal intestinal activity.

DOSAGE & ADMINISTRATION

Children over 12 years and Adults: 1 or 2 tablets, 3 times/day before meals.

INTERACTION

No other drug interactions have been observed during clinical trials or otherwise reported.

SIDE EFFECTS

Trimebutine Maleate is generally well tolerated. The infrequently reported adverse effects are as follows: dry mouth, foul taste, diarrhea, dyspepsia, epigastric pain, nausea, constipation, drowsiness, fatigue, dizziness, hot/cold sensations, headache etc.

PREGNANCY & LACTATION

Although teratological studies have not shown any drug related adverse effects on the course and outcome of pregnancy, the use of Trimebutine Maleate in pregnant women is not recommended. It is not known ifTrimebutine Maleate passes into breast milk. This medication should be used while breast feeding only if the potential benefits outweigh risks to the nursing infants.