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DBID
Registration ID: 176322642
Trade License: TRAD/DNCC/040904/2023

Opsonin Pharma Ltd. · Ophthalmic Solution
/ 5 ml drop
The information provided on All Samadhan is intended for general informational purposes only and is prepared based on our best practices. It is not a substitute for professional medical advice, diagnosis, or treatment. While we strive to keep the information accurate and up to date, we do not guarantee its completeness or accuracy. The absence of specific information or warnings about any medicine or service should not be considered as an assurance or endorsement by All Samadhan. All Samadhan shall not be held responsible for any consequences arising from the use of this information. We strongly recommend consulting a qualified healthcare professional or physician for any medical concerns, questions, or clarifications.
This sterile eye drops is indicated for the treatment of elevated intraocular pressure in patients with open angle glaucoma or ocular hypertension who are insufficiently responsive to topical beta blockers.
Dorzolamide Hydrochloride and Timolol Maleate reduce intraocular pressure (IOP) by combined action. Dorzolamide is human carbonic anhydrase II inhibitor which decreases aqueous humor secretion by slowing the formation of bicarbonate ions with subsequent reduction in sodium and fluid transport. Timolol is a non-selective beta adrenergic receptor blocker that does not have significant intrinsic sympathomimetic, direct myocardial depressant, or local anesthetic (membrane stabilizing) activity. It lowers IOP by decreasing the formation of aqueous humor in the ciliary epithelium.
Instill one drop in the conjunctival sac of the affected eye(s) twice daily.Use in children: Safety and effectiveness in children below the age of 2 years have not been established. Use in elderly patients: No overall differences in safety and effectiveness have been observed between elderly and other adult patients.
Additive hypotension and bradycardia with oral calcium channel blockers, catecholamine-depleting drugs or β-blockers, antiarrhythmics (e.g. amiodarone), digitalis glycosides, parasympathomimetics, narcotics and MAOIs. Additive systemic side effects with oral carbonic anhydrase or β-blockers; avoid concurrent use. Additive systemic β-blockade with CYP2D6 inhibitors (e.g. quinidine, SSRIs) and timolol.
Mild burning, ocular hyperemia, blurred vision may occur.
Use in pregnancy: There are no adequate and well-controlled studies in pregnant women. This Eye Drops should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus. Use in lactation: Caution should be exercised when This Eye Drops is administered to a nursing mother.
For ophthalmic use only. Patients should remove their contact lenses prior to instilling this preparation and should not insert their lenses until 15 minutes after instillation of the preparation.
Drugs for miotics and glaucoma
Store in a cool & dry place, protect from light. Do not use longer than one month after first opening. Keep out of the reach of children.