Seravent 25 mcg/puff is a Product of the Generic Salmeterol Xinafoate

Seravent 25 mcg/puff belongs to the generic category of Salmeterol Xinafoate. This medicine should be used according to a doctor's advice. We have provided detailed information about the uses, dosage, effectiveness, side effects, precautions, drug interactions, storage conditions, and other important details of Seravent 25 mcg/puff. Our goal is to present essential medicine information in one place for patients, caregivers, and healthcare professionals. To better understand Salmeterol Xinafoate and ensure the safe use of this medicine, please read the information below carefully and consult a healthcare professional when necessary.

Description of Seravent 25 mcg/puff

Seravent 25 mcg/puff may be available as a prescription or over-the-counter medicine, depending on local regulations and medical recommendations. It is used for the treatment and management of specific conditions or symptoms. The way this medicine is used may vary depending on the patient's condition and the advice of a healthcare provider. Detailed information about the approved uses, therapeutic applications, and other relevant details of Seravent 25 mcg/puff is provided below to help users gain a clear understanding of this medicine.

What Is Seravent 25 mcg/puff Indications and Uses?

Salmeterol Xinafoate is indicated for reversible airways obstruction (including nocturnal asthma and prevention of exercise-included bronchospasm) in patients requiring long term regular bronchodilator therapy.

Pharmacology (Source, Chemical and Physical Composition) Of Seravent 25 mcg/puff

Beta-2 adrenoceptor stimulation causes relaxation of bronchial smooth muscle, bronchodilation, and increased airflow. Salmeterol is hypothesized to bind to 2 sites on the beta-2 adrenoceptor.1 The saligenin moiety binds to the active site of the beta-2 adrenoceptor. The hydrophilic tail of salmeterol binds to leucine residues in the exo-site of the beta-2 adrenoceptor almost irreversibly, allowing salmeterol to persist in the active site, which is responsible for it's long duration of action. Another hypothesis is that the lipophilic drug diffuses into lipid bilayer of smooth muscle cells and provides a depot of drug to the cells over a longer period of time.

Dosage And Administration of Seravent 25 mcg/puff

Adults: 50 micrograms (two puffs) twice daily. More severe cases: 100 micrograms (four puffs) twice daily. Children 5-12 years: 50 micrograms (two puffs) twice daily. Or, as directed by the registered physician.

Drug Interactions of Seravent 25 mcg/puff

Monoamine Oxidase inhibitors and Tricyclic Antidepressants: These agents should be used with caution because Salmeterol may be potentiated by these agents.

Side Effects of Seravent 25 mcg/puff

Adverse effects which have been associated with Seravent are dose related tremor, subjective palpitations and headaches are usually mild and transient, muscle pain, stiffness, chest pain, rash have also been reported.

Use During Pregnancy and Lactation

Salmeterol should not be used in pregnant women except in clinical circumstance where no alternative therapy is appropriate and the potential benefit justifies the potential risk to the fetus. There are no date on the excretion of Salmeterol in human milk. A decision should be made to discontinue nursing or discontinue the drug, taking into account the importance of the drug to the mother.

Precautions And Warnings for Seravent 25 mcg/puff

Inhalation of Salmeterol may be associated with paradoxical bronchospasm and it should not be used in patients who are not also receiving and inhaled corticosteroid. Salmeterol is not appropriate for the treatment of acute symptoms.

Therapeutic Class

Long-acting selective β-adrenoceptor stimulants

Storage Conditions of It

Store between 20-25°C. Protect from heat or sunlight. Keep out of reach of children.

Seravent 25 mcg/puff is a Product of the Generic Salmeterol Xinafoate