Sefur IV 1.5 gm/vial is a Product of the Generic Cefuroxime Axetil

What Is Sefur IV 1.5 gm/vial Indications and Uses?

It is indicated for the treatment of infections caused by sensitive bacteria. Pharyngitis/Tonsillitis caused by Streptococcus pyogenes. Acute Bacterial Otitis Media caused by Streptococcus pneumoniae, Haemophilus influenzae, Moraxella catarrhalis (beta-lactamase producing strains) or Streptococcus pyogenes. ... Read more It is indicated for the treatment of infections caused by sensitive bacteria. Pharyngitis/Tonsillitis caused by Streptococcus pyogenes. Acute Bacterial Otitis Media caused by Streptococcus pneumoniae, Haemophilus influenzae, Moraxella catarrhalis (beta-lactamase producing strains) or Streptococcus pyogenes. Acute bacterial maxillary sinusitis caused by Streptococcus pneumoniae or Haemophilus influenzae (non beta-lactamase producing strains) Lower respiratory tract infections including pneumoniae, caused by Streptococcus pneumoniae, Haemophilus influenzae (including beta lactamase-producing strains), Klebsiella spp., Staphylococcus aureus (penicillinase- and non-penicillinase-producing strains), Streptococcus pyogenes, E. coli Acute bacterial exacerbation of chronic bronchitis and Secondary bacterial infections of Acute bronchitis caused by Streptococcus pneumoniae, Haemophilus influenzae (beta-lactamase negative strains) or Haemophilus parainfluenzae (beta-lactamase negative strains). Skin and skin-structure infections caused by Staphylococcus aureus (including beta-lactamase producing strains) or Streptococcus pyogenes. Urinary tract infections caused by E.coli or Klebsiella pneumoniae. Bone and Joint Infections caused by Staphylococcus aureus (penicillinase- and non-penicillinase-producing strains). Gonorrhoea caused by penicillinase-producing and non-penicillinase producing strains of Neisseria gonorrhoeae. Early Lyme Disease (erythema migrans) caused by Borrelia burgdorferi.

Pharmacology (Source, Chemical and Physical Composition) Of Sefur IV 1.5 gm/vial

Sefur IV 1.5 gm/vial (Cefuroxime Axetil) is a well-characterized and effective antibacterial agent, which has broad-spectrum bactericidal activity against a wide range of common pathogens, including β-lactamase producing strains. Cefuroxime has good stability to bacterial β-lactamase and consequently, is active against many ampicillin-resistant and amoxycillin-resistant strains.

Drug Interactions of Sefur IV 1.5 gm/vial

No potentially hazardous interactions have been reported.

Side Effects of Sefur IV 1.5 gm/vial

Adverse effects to Sefur have occurred infrequently and have been generally mild and transient in nature. Effects reported include rashes and gastrointestinal disturbances. As with other antibiotics, prolonged use may result in the overgrowth of non susceptible organisms e.g. Candida.

Precautions And Warnings for Sefur IV 1.5 gm/vial

Sefur should be given with care to patients receiving concurrent treatment with potent diuretics & who has history of colitis. Cephalosporin antibiotics may in general be given safely to patients who are hypersensitive to penicillin although cross reactions have reported. Sefur has shown, that is not likely to be a problem at the recommended to dose levels.

Use During Pregnancy and Lactation

US FDA pregnancy category of Sefur IV 1.5 gm/vial (Cefuroxime Axetil) is B. There are, however, no adequate and well-controlled studies in pregnant women. Because animal reproduction studies are not always predictive of human response, this drug should be used during pregnancy only if clearly needed. Cefuroxime have been shown to be excreted in human milk. So, caution should be exercised when Cefuroxime is administered to a nursing woman.

Therapeutic Class

Second generation cephalosporins

Storage Conditions of It

Store in a cool, dry place (below 30 o C), away from light & moisture. Keep out of the reach of children. Pack Image: Sefur 1.5 gm/vial Injection Thanks for using MedEx! How would you rate your experience so far?