Seemacillin Pediatric Drops Pediatric Drop 125 mg/1.25 ml is a Product of the Generic Ampicillin Sodium

What Is Seemacillin Pediatric Drops Pediatric Drop 125 mg/1.25 ml Indications and Uses?

Seemacillin is indicated in the treatment of infections caused by susceptible strains of the designated organism listed below: Infections of the Genitourinary Tract Including Gonorrhea : E. coli, P. mirabilis, enterococci, Shigella, S. typhosa and other Salmonella, and nonpenicillinase-producing N. gononhoeae. ... Read more Seemacillin is indicated in the treatment of infections caused by susceptible strains of the designated organism listed below: Infections of the Genitourinary Tract Including Gonorrhea : E. coli, P. mirabilis, enterococci, Shigella, S. typhosa and other Salmonella, and nonpenicillinase-producing N. gononhoeae. Infections of the Respiratory Tract : Nonpenicillinase-producing H. influenzae and staphylococci, and streptococci including streptococcus pneumoniae. Infections of the Gastrointestinal Tract : Shigella, S. typhosa and other Salmonella, E. coli, P. mirabilis, and enterococci. Meningitis : O. Meningitides. Bacteriology studies to determine the causative organisms and their sensetivity to Seemacillin Pediatric Drops Pediatric Drop 125 mg/1.25 ml (Ampicillin Sodium) should be performed. Therapy may be instituted prior to the results of susceptibility testing.

Pharmacology (Source, Chemical and Physical Composition) Of Seemacillin Pediatric Drops Pediatric Drop 125 mg/1.25 ml

Seemacillin Pediatric Drops Pediatric Drop 125 mg/1.25 ml (Ampicillin Sodium) inhibits bacterial cell wall synthesis by binding to 1 or more of the penicillin-binding proteins (PBPs) which in turn inhibit the final transpeptidation step of peptidoglycan synthesis in bacterial cell walls. Bacteria eventually lyse due to ongoing activity of cell wall autolytic enzymes (autolysins and murein hydrolases) while cell wall assembly is arrested.

Drug Interactions of Seemacillin Pediatric Drops Pediatric Drop 125 mg/1.25 ml

May reduce the efficacy of oral contraceptives. May alter INR while on warfarin and phenindione. May reduce the efficacy of oral typhoid vaccines. May reduce the excretion of methotrexate. Reduced excretion with probenecid and sulfinpyrazone, resulting to increased risk of toxicity. Allopurinol increases ampicillin-induced skin reactions. Reduced absorption with chloroquine. Bacteriostatic antibacterials (e.g. erythromycin, chloramphenicol, tetracycline) may interfere with the bactericidal action of Seemacillin Pediatric Drops Pediatric Drop 125 mg/1.25 ml (Ampicillin Sodium).

Side Effects of Seemacillin Pediatric Drops Pediatric Drop 125 mg/1.25 ml

Nausea, vomiting, diarrhoea, erythematous maculo-papular rashes, sore mouth, black/hairy tongue, rash, erythema multiforme, Stevens-Johnson syndrome, toxic epidermal necrolysis, angioedema, fever, joint pains, serum sickness-like symptoms, haemolytic anaemia, thrombocytopenia, leucopenia, neutropenia, coagulation disorders, prolonged bleeding time and prothrombin time, CNS toxicity (e.g. convulsions); paraesthesia, nephropathy, interstitial nephritis, hepatitis, cholestatic jaundice, moderate and transient increase in transaminases, Anaphylaxis, Clostridium difficile-associated diarrhoea (CDAD).

Precautions And Warnings for Seemacillin Pediatric Drops Pediatric Drop 125 mg/1.25 ml

Patient with history of β-lactam allergy. During renal impairment, Pregnancy and lactation.

Use During Pregnancy and Lactation

Pregnancy Category B. Either animal-reproduction studies have not demonstrated a fetal risk but there are no controlled studies in pregnant women or animal-reproduction studies have shown an adverse effect (other than a decrease in fertility) that was not confirmed in controlled studies in women in the 1st trimester (and there is no evidence of a risk in later trimesters).

Storage Conditions of It

Store between 20-25° C. Reconstituted oral susp: Store between 2-8° C (discard after 14 days). Thanks for using MedEx! How would you rate your experience so far?