Rivastigmine Amneal 13.3 mg/24 hr is a Product of the Generic Rivastigmine Tartrate

Rivastigmine Amneal 13.3 mg/24 hr belongs to the generic category of Rivastigmine Tartrate. This medicine should be used according to a doctor's advice. We have provided detailed information about the uses, dosage, effectiveness, side effects, precautions, drug interactions, storage conditions, and other important details of Rivastigmine Amneal 13.3 mg/24 hr. Our goal is to present essential medicine information in one place for patients, caregivers, and healthcare professionals. To better understand Rivastigmine Tartrate and ensure the safe use of this medicine, please read the information below carefully and consult a healthcare professional when necessary.

Description of Rivastigmine Amneal 13.3 mg/24 hr

Rivastigmine Amneal 13.3 mg/24 hr may be available as a prescription or over-the-counter medicine, depending on local regulations and medical recommendations. It is used for the treatment and management of specific conditions or symptoms. The way this medicine is used may vary depending on the patient's condition and the advice of a healthcare provider. Detailed information about the approved uses, therapeutic applications, and other relevant details of Rivastigmine Amneal 13.3 mg/24 hr is provided below to help users gain a clear understanding of this medicine.

What Is Rivastigmine Amneal 13.3 mg/24 hr Indications and Uses?

Rivastigmine Amneal 13.3 mg/24 hr (Rivastigmine Tartrate) Amneal is indicated for the symptomatic treatment of mild to moderately severe Alzheimer's dementia. Symptomatic treatment of mild to moderately severe dementia in patients with Idiopathic Parkinson's disease.

Pharmacology (Source, Chemical and Physical Composition) Of Rivastigmine Amneal 13.3 mg/24 hr

Rivastigmine Amneal 13.3 mg/24 hr (Rivastigmine Tartrate) is a carbamate derivative that is structurally related to physostigmine, but not to donepezil and tacrine. The precise mechanism of rivastigmine has not been fully determined, but it is suggested that rivastigmine binds reversibly with and inactivates chlolinesterase (eg. acetylcholinesterase, butyrylcholinesterase), preventing the hydrolysis of acetycholine, and thus leading to an increased concentration of acetylcholine at cholinergic synapses. The anticholinesterase activity of rivastigmine is relatively specific for brain acetylcholinesterase and butyrylcholinesterase compared with those in peripheral tissues.

Drug Interactions of Rivastigmine Amneal 13.3 mg/24 hr

As a cholinesterase inhibitor, Rivastigmine Amneal 13.3 mg/24 hr (Rivastigmine Tartrate) may exaggerate the effects of succinylcholine-type muscle relaxants during anaesthesia. Caution is recommended when selecting anaesthetic agents. Possible dose adjustments or temporarily stopping treatment can be considered if needed. In view of its pharmacodynamic effects, rivastigmine should not be given concomitantly with other cholinomimetic substances and might interfere with the activity of anticholinergic medicinal products. No pharmacokinetic interaction was observed between rivastigmine and digoxin, warfarin, diazepam or fluoxetine in studies in healthy volunteers. The increase in prothrombin time induced by warfarin is not affected by administration of rivastigmine. No untoward effects on cardiac conduction were observed following concomitant administration of digoxin and Rivastigmine Amneal.

Side Effects of Rivastigmine Amneal 13.3 mg/24 hr

The most commonly reported adverse reactions are gastrointestinal, including nausea (38%) and vomiting (23%), especially during titration. Female patients in clinical studies were found to be more susceptible than male patients to gastrointestinal adverse reactions and weight loss.

Precautions And Warnings for Rivastigmine Amneal 13.3 mg/24 hr

Patients with sick sinus syndrome or conduction defects, resp diseases. Cholinergic stimulation may increase gastric acid secretion. May exacerbate urinary obstruction and seizures. Pregnancy. Renal impairment, mild to moderate hepatic impairment. Monitor body wt. Asthma or obstructive pulmonary disease. May worsen extrapyramidal symptoms. Lactation.

Use During Pregnancy and Lactation

For Rivastigmine Amneal 13.3 mg/24 hr (Rivastigmine Tartrate) no clinical data are available. Rivastigmine should not be used during pregnancy unless clearly necessary. In animals, rivastigmine is excreted into milk. It is not known if rivastigmine is excreted into human milk. Therefore, women on rivastigmine should not breast-feed.

Therapeutic Class

Drugs for Dementia

Storage Conditions of It

Store in a cool and dry place, protected from light. Pack Image: Rivastigmine Amneal 13.3 mg/24 hr Transdermal Patch Thanks for using MedEx! How would you rate your experience so far?