Provigor 10 mg is a Product of the Generic Vardenafil

What Is Provigor 10 mg Indications and Uses?

Provigor 10 mg (Vardenafil) is used to treat erectile dysfunction (ED).

Pharmacology (Source, Chemical and Physical Composition) Of Provigor 10 mg

Provigor 10 mg (Vardenafil) is a selective inhibitor of cyclic guanosine monophosphate (cGMP) specific phosphodiesterase type 5 (PDE5). Penile erection is a hemodynamic process initiated by the relaxation of smooth muscle in the corpus cavernosum and its associated arterioles. During sexual stimulation, nitric oxide is released in the corpus cavernosum & activates the enzyme guanylate cyclase resulting in increased synthesis of cyclic guanosine monophosphate (cGMP) in the smooth muscle cells of the corpus cavernosum. The cGMP in turn triggers smooth muscle relaxation, allowing increased blood flow into the penis, resulting in an erection. Inhibition of PDE5 enhances erectile function by increasing the amount of cGMP. Because sexual stimulation is required to initiate the local release of nitric oxide, the inhibition of PDE5 has no effect in the absence of sexual stimulation.

Dosage And Administration of Provigor 10 mg

The recommended starting dose : 10 mg once daily, taken orally approximately 60 minutes before sexual activity. The dose may be increased to a maximum dose of 20 mg or decreased to 5 mg based on efficacy and side effects. The maximum recommended dosing frequency is once per day. Provigor 10 mg (Vardenafil) can be taken with or without food. Geriatrics : A starting dose of 5 mg should be considered in patients >65 years of age. Renal impaired patients : In patients with renal impairment, no dose adjustment is required. Hepatic impaired patients : In patients with moderate hepatic impairment, a starting dose of 5 mg is recommended and the maximum dose should not exceed 10 mg. Do not use in patients with severe hepatic impairment.

Drug Interactions of Provigor 10 mg

Provigor 10 mg (Vardenafil) can potentiate the blood pressure lowering effect of antihypertensive agents. In clinical studies, single doses of Provigor 20 mg caused a mean decrease in blood pressure of 7 mmHg systolic and 8 mmHg diastolic. Caution should be taken when co-administered with other vasodilators including alpha blockers. Provigor does not potentiate the hypotensive effect of alcohol. CYP3A4 inhibitors (ketoconazole, indinavir, ritonavir and erythromycin) may reduce Provigor excretion from body

Side Effects of Provigor 10 mg

The most common side effects with Provigor 10 mg (Vardenafil) are headache, flushing, stuffy or runny nose, indigestion, upset stomach, dizziness or back pain.

Precautions And Warnings for Provigor 10 mg

Physicians should consider the cardiovascular status of their patients, since there is a degree of cardiac risk associated with sexual activity. In men for whom sexual activity is not recommended because of their underlying cardiovascular status, Provigor 10 mg (Vardenafil) generally should not be used.

Use During Pregnancy and Lactation

Provigor 10 mg (Vardenafil) is not indicated for women.

Therapeutic Class

Drugs for Erectile Dysfunction

Storage Conditions of It

Store at room temperature and protect from light and moisture. Keep out of the reach of children. Pack Image: Provigor 10 mg Tablet Thanks for using MedEx! How would you rate your experience so far?