OTC

Proston 0.5 mg/3 gm

Renata PLC · Vaginal Gel

GenericDinoprostone

Strength0.5 mg/3 gm

Unit Price

৳ 200

/ 3 gm tube

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⚠ Disclaimer

The information provided on All Samadhan is intended for general informational purposes only and is prepared based on our best practices. It is not a substitute for professional medical advice, diagnosis, or treatment. While we strive to keep the information accurate and up to date, we do not guarantee its completeness or accuracy. The absence of specific information or warnings about any medicine or service should not be considered as an assurance or endorsement by All Samadhan. All Samadhan shall not be held responsible for any consequences arising from the use of this information. We strongly recommend consulting a qualified healthcare professional or physician for any medical concerns, questions, or clarifications.

Medicine Description

INDICATIONS

Dinoprostone is indicated to helps in the induction of labor, and widens the cervix for easy delivery. It is also used to initiate an abortion at about 12 to 20 weeks of pregnancy and also indicated to help clean out the vagina after a miscarriage.

PHARMACOLOGY

Dinoprostone is a naturally-occurring biomolecule. It functions as a local hormone. Dinoprostone causes the cervix muscles to dilate and become relaxed. This eventually encourages the muscle of uterus to contract during labour. Its functions are similar to that of PG E-2 or Prostaglandin E2.

DOSAGE & ADMINISTRATION

For adult patients: The recommended dose of Dinoprostone gel is 0.5 mg. After placement of the gel, the patient should be instructed to remain in the dorsal position for 10-15 minutes to minimize gel leakage.Geriatrics (>65 years of age): Dinoprostone gel has not been studied in this patient population and is not recommended for use.Pediatrics (<18 years of age): Dinoprostone gel has not been studied in this patient population and is not recommended for use.

INTERACTION

With Medicine: It is not advised to use Dinoprostone concurrently with oxytocic medications, since it may increase their action. For the successive use of oxytocin after removing the Dinoprostone vaginal insert, a dosage interval of at least 30 minutes is advised. There are no known interactions between other drugs.With Food and Others: Dinoprostone is known to interact with alcohol. So, do not consume alcohol while using Dinoprostone.

SIDE EFFECTS

Common: Abnormal Labor Affecting Fetus, Fetal Heart Rate Disorder, Fetal Distress Syndrome, Uterine Hypertonus.Uncommon: Nausea, Vomiting, Fever, Abdominal Pain, Diarrhea.Rare: Disseminated Intravascular Coagulation, Uterine Rupture, Anaphylactic Reaction.

PREGNANCY & LACTATION

Dinoprostone classified in FDA pregnancy category C. It is not recommended during pregnancy, labor or delivery and in mothers who are breast feeding.

PRECAUTIONS & WARNINGS

Caution should be exercised in administration of Dinoprostone Gel in patients with: Hypertonus, Sustained Uterine Contractility or Fetal Distress, Hypertonic Uterine Contractility or Tetanic Uterine Contractions, Asthma, Glaucoma, Heart Diseases, Depression.