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Copyright © All Samadhan - Operated by M/S. Genius Experts | All Rights Reserved
DBID
Registration ID: 176322642
Trade License: TRAD/DNCC/040904/2023
Copyright © All Samadhan - Operated by M/S. Genius Experts | All Rights Reserved
DBID
Registration ID: 176322642
Trade License: TRAD/DNCC/040904/2023
General Pharmaceuticals Ltd. · Cream
/ 20 gm tube
The information provided on All Samadhan is intended for general informational purposes only and is prepared based on our best practices. It is not a substitute for professional medical advice, diagnosis, or treatment. While we strive to keep the information accurate and up to date, we do not guarantee its completeness or accuracy. The absence of specific information or warnings about any medicine or service should not be considered as an assurance or endorsement by All Samadhan. All Samadhan shall not be held responsible for any consequences arising from the use of this information. We strongly recommend consulting a qualified healthcare professional or physician for any medical concerns, questions, or clarifications.
Capsaicin is indicated for the symptomatic relief of pain associated with osteoarthritis and rheumatoid arthritis.
Although the precise mechanism of action of Capsaicin is not fully understood, current evidence suggests that Capsaicin exerts an analgesic effect by depleting and preventing reaccumulation of Substance P in peripheral sensory neurons. Substance P is thought to be the principal chemomediator of pain impulses from the periphery to the central nervous system. Absorption after topical application is unknown. Capsaicin content in capsicum fruit is approximately 1% therefore dietary intake of Capsaicin may range from 0.5-1mg/kg/day for a 50kg person. Application of 90 gm of Capsaicin cream 0.025% each week results in 3.21mg/day topical exposure. Assuming 100% absorption in a 50kg person, daily exposure would be 0.064mg/kg which is approximately one eighth of the above mentioned dietary intake.
18 years of age and older: Apply a thin film of Capsaicin cream to affected area 3 to 4 times daily. A burning sensation may occur upon application, but generally disappears with regular use. Application schedules of 3 to 4 times a day for 2 weeks provides optimum pain relief.
Transient burning sensation may occur during initial treatment, particularly if too much cream is used or if the frequency of administration is less than 3-4 times daily. This burning sensation generally disappears after several days of treatment.
The safety of Capsaicin during pregnancy and lactation has not been established, in either humans or animals. However, in the small amounts absorbed transdermally from Capsaicin cream, it is considered unlikely that Capsaicin will cause any adverse effects in humans.
Avoid taking a hot shower or bath just before or after applying Capsaicin burning sensation may enhance. Hands should be washed immediately after use. Not for use under tight bandages.
Topical Analgesics, Topical anti-inflammatory preparations
Keep below 30°C temperature, away from light & moisture. Keep out of the reach of children.