Orzolol 2%+0.5% is a Product of the Generic Dorzolamide + Timolol

Orzolol 2%+0.5% belongs to the generic category of Dorzolamide + Timolol. This medicine should be used according to a doctor's advice. We have provided detailed information about the uses, dosage, effectiveness, side effects, precautions, drug interactions, storage conditions, and other important details of Orzolol 2%+0.5%. Our goal is to present essential medicine information in one place for patients, caregivers, and healthcare professionals. To better understand Dorzolamide + Timolol and ensure the safe use of this medicine, please read the information below carefully and consult a healthcare professional when necessary.

Description of Orzolol 2%+0.5%

Orzolol 2%+0.5% may be available as a prescription or over-the-counter medicine, depending on local regulations and medical recommendations. It is used for the treatment and management of specific conditions or symptoms. The way this medicine is used may vary depending on the patient's condition and the advice of a healthcare provider. Detailed information about the approved uses, therapeutic applications, and other relevant details of Orzolol 2%+0.5% is provided below to help users gain a clear understanding of this medicine.

What Is Orzolol 2%+0.5% Indications and Uses?

This sterile eye drops is indicated for the treatment of elevated intraocular pressure in patients with open angle glaucoma or ocular hypertension who are insufficiently responsive to topical beta blockers.

Pharmacology (Source, Chemical and Physical Composition) Of Orzolol 2%+0.5%

Dorzolamide Hydrochloride and Timolol Maleate reduce intraocular pressure (IOP) by combined action. Dorzolamide is human carbonic anhydrase II inhibitor which decreases aqueous humor secretion by slowing the formation of bicarbonate ions with subsequent reduction in sodium and fluid transport. Timolol is a non-selective beta adrenergic receptor blocker that does not have significant intrinsic sympathomimetic, direct myocardial depressant, or local anesthetic (membrane stabilizing) activity. It lowers IOP by decreasing the formation of aqueous humor in the ciliary epithelium.

Dosage And Administration of Orzolol 2%+0.5%

Instill one drop in the conjunctival sac of the affected eye(s) twice daily.Use in children: Safety and effectiveness in children below the age of 2 years have not been established. Use in elderly patients: No overall differences in safety and effectiveness have been observed between elderly and other adult patients.

Drug Interactions of Orzolol 2%+0.5%

Additive hypotension and bradycardia with oral calcium channel blockers, catecholamine-depleting drugs or β-blockers, antiarrhythmics (e.g. amiodarone), digitalis glycosides, parasympathomimetics, narcotics and MAOIs. Additive systemic side effects with oral carbonic anhydrase or β-blockers; avoid concurrent use. Additive systemic β-blockade with CYP2D6 inhibitors (e.g. quinidine, SSRIs) and timolol.

Side Effects of Orzolol 2%+0.5%

Mild burning, ocular hyperemia, blurred vision may occur.

Use During Pregnancy and Lactation

Use in pregnancy: There are no adequate and well-controlled studies in pregnant women. This Eye Drops should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus. Use in lactation: Caution should be exercised when This Eye Drops is administered to a nursing mother.

Precautions And Warnings for Orzolol 2%+0.5%

For ophthalmic use only. Patients should remove their contact lenses prior to instilling this preparation and should not insert their lenses until 15 minutes after instillation of the preparation.

Therapeutic Class

Drugs for miotics and glaucoma

Storage Conditions of It

Store in a cool & dry place, protect from light. Do not use longer than one month after first opening. Keep out of the reach of children.

Orzolol 2%+0.5% is a Product of the Generic Dorzolamide + Timolol

Orzolol 2%+0.5%

OSL Pharma Limited · Ophthalmic Solution

Dorzolamide + Timolol