Ofkof (10 mg+30 mg+1.25 mg)/5 ml is a Product of the Generic Dextromethorphan + Pseudoephedrine + Triprolidine

What Is Ofkof (10 mg+30 mg+1.25 mg)/5 ml Indications and Uses?

This preparation temporarily relieves these symptoms due to common cold, hay fever (allergic rhinitis) or other upper respiratory allergies:

Non-productive cough due to minor throat or bronchial irritation
Runny Nose
Sneezing
Itching of the nose or throat
Itchy & watery eyes
Nasal congestion

Pharmacology (Source, Chemical and Physical Composition) Of Ofkof (10 mg+30 mg+1.25 mg)/5 ml

This preparation is a mixture of antitussive, decongestant and antihistamine agent. Dextromethorphan is a safe, effective, non-narcotic antitussive agent which has a central action on the cough centre in the medulla. Although structurally related to Morphine, it has no analgesic and habit forming properties and in general it has little sedative activity. Phenylephrine is a decongestant that shrinks blood vessels in the nasal passage. Phenylephrine is used for the temporary relief of stuffy nose, sinus, and ear symptoms caused by the common cold, flu, allergies, sinusitis & bronchitis. This medication works by decreasing swelling in the nose and ears, thereby lessening discomfort and making it easier to breathe. Triprolidine is an antihistamine used to relieve symptoms of allergy, hay fever, and the common cold. These symptoms include rash, watery eyes, itchy eyes/nose/throat/skin, cough, runny nose, and sneezing. It is a potent competitive histamine H1-receptor antagonist of the pyrrolidine class with mild central nervous system depressant properties which may cause drowsiness. By antagonizing another natural substance acetylcholine, it helps dry up some body fluids to relieve symptoms such as watery eyes and runny nose.

Dosage And Administration of Ofkof (10 mg+30 mg+1.25 mg)/5 ml

Adults & Children over 12 years: 1 teaspoonful (5 ml) 4 times a day every 4 hours interval.6-12 years: 1/2 teaspoonful 4 times a day every 4 hours interval.Use in children and adolescents: A physician's advice should be obtained before administering this combination to children less than 6 years.

Drug Interactions of Ofkof (10 mg+30 mg+1.25 mg)/5 ml

Taking certain MAO inhibitors with this medication may cause a serious (possibly fatal) drug interaction. Avoid taking isocarboxazid, methylene blue, moclobemide, phenelzine, procarbazine, rasagiline, selegiline, or tranylcypromine during treatment with this medication. Most MAO inhibitors should also not be taken for two weeks before treatment with this medication.

Side Effects of Ofkof (10 mg+30 mg+1.25 mg)/5 ml

It may cause drowsiness and constipation. Other side effects that may occur include GIT discomfort. No apparent evidence of physical dependence of the morphine type.

Use During Pregnancy and Lactation

There are no specific data on use of this combination during pregnancy & lactation.

Precautions And Warnings for Ofkof (10 mg+30 mg+1.25 mg)/5 ml

This preparation may cause drowsiness. If affected, do not drive motor vehicle or operate machinery. Avoid alcoholic drink while on this medication. Use with caution in patients with epilepsy, prostatic hypertrophy, glaucoma, hepatic disease, hypertension, heart disease, diabetes, hyperthyroidism. If symptoms do not improve within one week or accompanied with high fever, consult a physician before continuing use.

Therapeutic Class

Combined cough suppressants

Storage Conditions of It

Store in a cool and dry place (below 30°C temperature), away from light. Keep out of the reach of children.