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DBID
Registration ID: 176322642
Trade License: TRAD/DNCC/040904/2023
Copyright © All Samadhan - Operated by M/S. Genius Experts | All Rights Reserved
DBID
Registration ID: 176322642
Trade License: TRAD/DNCC/040904/2023
Jayson Pharmaceutical Ltd. · Injection
/ Piece
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Nikethamide is indicated in-
Acute respiratory failure
Respiratory depression following anesthesia
CNS depression
Nikethamide also known as nicotinic acid diethylamide is a central & respiratory stimulant. It has direct stimulatory action on CNS, increases the frequency & depth of breathing. It has no immediate impact on the cardiovascular system. It is extensively metabolized in liver. All metabolites & a small amount of unchanged drug is excreted in urine.
2 to 10 mL by slow IV injection of the usual 25% solution every 20 to 30 minutes if necessary. Infants and children are particularly susceptible to toxic effects of nikethamide.
Anesthetic, sympathomimetics, MAOIs, neuromuscular blockers, bupropion.
Dyspnoea, respiratory problems such as coughing bronchospasm. Other CNS side effects include convulsion, headache & dizziness. Cardiovascular side effects inlude Iteration of blood pressure & cardiac arrhythmia. Over dosage may cause nausea, vomiting & diarrhoea.
There are no enough adequate and controlled studies in pregnant women and nursing mothers.
It should not used in less severe degrees of hypertension or impaired cardiac reverse & hepatic dysfunction.
Respiratory stimulants: analeptics
Store below 25°C in a dry place, away from light.