Nepofer 27.2 mg/5 ml is a Product of the Generic Ferric Pyrophosphate Citrate

Nepofer 27.2 mg/5 ml belongs to the generic category of Ferric Pyrophosphate Citrate. This medicine should be used according to a doctor's advice. We have provided detailed information about the uses, dosage, effectiveness, side effects, precautions, drug interactions, storage conditions, and other important details of Nepofer 27.2 mg/5 ml. Our goal is to present essential medicine information in one place for patients, caregivers, and healthcare professionals. To better understand Ferric Pyrophosphate Citrate and ensure the safe use of this medicine, please read the information below carefully and consult a healthcare professional when necessary.

Description of Nepofer 27.2 mg/5 ml

Nepofer 27.2 mg/5 ml may be available as a prescription or over-the-counter medicine, depending on local regulations and medical recommendations. It is used for the treatment and management of specific conditions or symptoms. The way this medicine is used may vary depending on the patient's condition and the advice of a healthcare provider. Detailed information about the approved uses, therapeutic applications, and other relevant details of Nepofer 27.2 mg/5 ml is provided below to help users gain a clear understanding of this medicine.

What Is Nepofer 27.2 mg/5 ml Indications and Uses?

Ferric Pyrophosphate Citrate is indicated for the replacement of iron to maintain hemoglobin in adult patients with hemodialysis-dependent chronic kidney disease (HDD-CKD).

Dosage And Administration of Nepofer 27.2 mg/5 ml

Inspect Ferric Pyrophosphate Citrate ampoule for signs of precipitation prior to mixing with the bicarbonate concentrate. Ferric Pyrophosphate Citrate should only be added to the bicarbonate concentrate and should not be added to acid concentrate mixtures. Add Ferric Pyrophosphate Citrate to bicarbonate concentrate used for generation of hemodialysate. The final concentration of iron (III) in the final hemodialysate is 2 micromolar (110 mcg/L). Multiple ampoules can be added to the master bicarbonate mix at each center at a ratio of one ampoule to each 2.5 gallons of bicarbonate concentrate.Administer Ferric Pyrophosphate Citrate to patients at each dialysis procedure for as long as patients are receiving maintenance hemodialysis therapy for CKD.Hemodialysis solutions should be used within 24 hours of the preparation of the Ferric Pyrophosphate Citrate /bicarbonate concentrate mixture.

Drug Interactions of Nepofer 27.2 mg/5 ml

Formal drug interaction studies have not been performed for Ferric Pyrophosphate Citrate.

Side Effects of Nepofer 27.2 mg/5 ml

The most common side effects are headache, peripheral edema, asthenia, AV fistula thrombosis, urinary tract infection, AV fistula site hemorrhage, pyrexia, fatigue, hypotension, muscle spasms, pain in extremity, back pain, and dyspnea.

Use During Pregnancy and Lactation

Pregnant women Category C. Lactating mothers It is not known whether Ferric Pyrophosphate Citrate is present in human milk or not.

Precautions And Warnings for Nepofer 27.2 mg/5 ml

Hypersensitivity Reactions: Anaphylactic-type reactions, shock, hypotension, loss of consciousness and collapse can occur. Monitor patients for signs and symptoms of hypersensitivity during and after hemodialysis until he/she is clinically stable. Personnel and therapies should be immediately available for the treatment of serious hypersensitivity reactions.Iron laboratory testing: Iron status should be determined on pre-dialysis blood samples. Post dialysis serum iron parameters may overestimate serum iron and transferrin saturation.

Therapeutic Class

Parenteral Iron Preparations

Storage Conditions of It

Keep in a cool and dry place, away from light. Keep out of reach of children.

Nepofer 27.2 mg/5 ml is a Product of the Generic Ferric Pyrophosphate Citrate