Nepanil TS 0.003

Nepanil TS 0.003 | INDICATIONS AND USES

Nepafenac 0.1% Sterile Ophthalmic Suspension: The treatment of post-operative ocular pain and inflammation including cataract surgery Inhibition of surgery induced miosis and Prevention of post-operative cystoid macular edema (CME).Nepafenac 0.3% Sterile Ophthalmic Suspension: Post-operative pain and inflammation associated with cataract surgery.

Nepanil TS 0.003 | PHARMACOLOGY

Nepafenac is a nonsteroidal anti-inflammatory prodrug (NSAID). After instillation in the eye, it penetrates the cornea and is converted by ocular tissue hydrolase to Amfenac, a potent nonsteroidal anti-inflammatory drug. Amfenac is thought to inhibit the action of cyclooxygenase enzyme. This enzyme is required for prostaglandin synthesis.

Nepanil TS 0.003 | DOSAGE & ADMINISTRATION

Nepafenac 0.1% Sterile Ophthalmic Suspension-

For post-operative pain & inflammation: Instill 1 drop 3 times daily 1 day prior to cataract surgery and continued on the day of surgery and through the first 2 weeks of the post-operative period.
For surgery induced miosis: Instill 1 drop 3 times daily 1 day before surgery & on the day of surgery.
For prevention of post-operative CME: Instill 1 drop 3 times daily 1 day before surgery and continued on the day of surgery and through the first 6 weeks of the post-operative period.

Nepafenac 0.3% Sterile Ophthalmic Suspension-

For post-operative pain & inflammation: Instill 1 drop once daily 1 day prior to cataract surgery and continued on the day of surgery and through the first 2 weeks of the post-operative period. An additional drop should be administered 30 to 120 minutes prior to surgery.

Nepanil TS 0.003 | SIDE EFFECTS

Reported side effects are foreign body sensation, lid margin crusting, ocular discomfort, ocular hyperemia etc.

Nepanil TS 0.003 | USE DURING PREGNANCY AND LACTATION

Use in pregnancy: There are no adequate and well-controlled studies in pregnant women. Nepafenac should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus.Use in lactation: It is not known whether this drug is excreted in human milk. So, caution should be exercised when Nepafenac ophthalmic suspension is administered to a nursing mother.

Nepanil TS 0.003 | PRECAUTIONS & WARNINGS

Nepafenac should be used with caution in patients with known bleeding tendencies or who are receiving medications which may prolong bleeding time.

Nepanil TS 0.003 | USE IN SPECIAL POPULATIONS

Use in children: Safety and effectiveness in pediatric patients below 18 years of age have not been established.Use in elderly patients: No overall differences in safety or effectiveness have been observed between elderly and younger patients.

Nepanil TS 0.003 | THERAPEUTIC CLASS

Ophthalmic Non-Steroid drugs