Neotison Dry Powder Inhalation Capsule (DPI) Inhalation Capsule 200 mcg is a Product of the Generic Fluticasone Furoate

What Is Neotison Dry Powder Inhalation Capsule (DPI) Inhalation Capsule 200 mcg Indications and Uses?

Neotison nasal spray is indicated for the treatment of the symptoms of seasonal and perennial allergic rhinitis in patients aged 2 years and older. Neotison inhalation powder is indicated for the once-daily maintenance treatment of asthma as prophylactic therapy in patients aged 5 years and older. This is not indicated for the relief of acute bronchospasm.

Pharmacology (Source, Chemical and Physical Composition) Of Neotison Dry Powder Inhalation Capsule (DPI) Inhalation Capsule 200 mcg

Neotison Dry Powder Inhalation Capsule (DPI) Inhalation Capsule 200 mcg (Fluticasone Furoate) is a synthetic trifluorinated corticosteroid with potent anti inflammatory activity. Like other corticosteroids Fluticasone Furoate is found to have a wide range of actions on multiple cell types (e.g., mast cells, eosinophils, neutrophils, macrophages, lymphocytes) and mediators (e.g.- histamine, eicosanoids, leukotrienes, cytokines) involved in inflammation.

Drug Interactions of Neotison Dry Powder Inhalation Capsule (DPI) Inhalation Capsule 200 mcg

Potent inhibitors of cytochrome P450 3A4 (CYP3A4) may increase exposure to Neotison. Coadministration of ritonavir is not recommended. Use caution with coadministration of other potent CYP3A4 inhibitors, such as ketoconazole. Special instruction: Patients should be instructed that the device must be primed: before first use, and if the cap is left off or if the device does not seem to be working or if the nasal spray has not been used for 30 days or more. In order to prime the device, the nasal spray needs to be shaken vigorously for about 10 seconds with the cap on. The patient must then press the button firmly all the way in, approximately 6 times until a fine mist is seen. Once primed, the patient must shake the nasal spray vigorously each time before use.

Side Effects of Neotison Dry Powder Inhalation Capsule (DPI) Inhalation Capsule 200 mcg

Neotison nasal spray is absorbed less into the rest of the body, therefore fewer side effects are seen. With the nasal spray, drying of the nose and an increase in the incidence of nosebleeds may occur. Most common adverse reactions of Neotison inhalation capsule reported in ≥5% of adult and adolescent subjects are nasopharyngitis, bronchitis, upper respiratory tract infection, and headache. Most common adverse reactions reported in ≥3% of pediatric subjects aged 5 to 11 years are pharyngitis, bronchitis, and viral infection.

Precautions And Warnings for Neotison Dry Powder Inhalation Capsule (DPI) Inhalation Capsule 200 mcg

Rarely, immediate hypersensitivity reactions or contact dermatitis may occur after the administration of Neotison nasal spray. Rare instances of wheezing, nasal septum perforation, cataracts, glaucoma and increased intraocular pressure have been reported following the intranasal application of corticosteroids, including Neotison. Although systemic effects have been minimal with recommended doses of Neotison nasal spray, potential risk increases with larger doses. Therefore, larger than recommended doses of Neotison nasal spray should be avoided.

Use During Pregnancy and Lactation

Use in pregnancy : Pregnancy category C. There are no adequate and well-controlled studies in pregnant women. Neotison Dry Powder Inhalation Capsule (DPI) Inhalation Capsule 200 mcg (Fluticasone Furoate) nasal spray should be used during pregnancy only if the potential benefit justifies the potential risk of the fetus. Use in lactation : It is not known whether Fluticasone Furoate is excreted in human breast milk. However, since other corticosteroids have been detected in human milk, caution should be exercised when Fluticasone Furoate is administered to a nursing woman.

Therapeutic Class

Nasal Steroid Preparations

Storage Conditions of It

Store at a temperature not exceeding 30°C. Do not refrigerate. Protect from light and moisture. Keep out of the reach of children. Pack Image: Neotison 200 mcg Inhalation Capsule Thanks for using MedEx! How would you rate your experience so far?