Nasochrom Ophthalmic Solution Eye Drop 0.02 is a Product of the Generic Sodium Cromoglicate [2%]

What Is Nasochrom Ophthalmic Solution Eye Drop 2% Indications and Uses?

Nasochrom Cromoglycate 2% Eye Drops is used for the prophylaxis and symptomatic treatment of certain allergic ocular disorders including vernal kerato conjunctivitis, vernal conjunctivitis, giant papillary conjunctivitis, vernal keratitis and allergic keratoconjunctivitis. Ophthalmic administration of ... Read more Nasochrom Cromoglycate 2% Eye Drops is used for the prophylaxis and symptomatic treatment of certain allergic ocular disorders including vernal kerato conjunctivitis, vernal conjunctivitis, giant papillary conjunctivitis, vernal keratitis and allergic keratoconjunctivitis. Ophthalmic administration of Nasochrom Cromoglycate 2% Eye Drops generally provides symptomatic relief of itching, tearing, redness and discharge within a few days following initiation of therapy; however, up to 6 weeks of therapy may be required for optimum symptomatic relief in some patients. Once symptomatic improvement has been established therapy should be continued for as long as needed to sustain improvement.

Pharmacology (Source, Chemical and Physical Composition) Of Nasochrom Ophthalmic Solution Eye Drop 2%

Nasochrom Ophthalmic Solution Eye Drop 2% (Sodium Cromoglicate [2%]) Cromoglycate 2% sterile Eye Drops inhibits the release of chemical mediators from sensitised mast cells and is capable of rapid phosphorylation of mast cell protein. The exact mechanism of action of the drug remains to be elucidated but Sodium Cromoglycate appears to modulate the allergic response to antigen antibody interactions in a way which prevents the subsequent formation or release of toxic or inflammatory mediators. Sodium Cromoglycate 2% Eye Drops appears to act mainly through a local effect on the mucous of the eye. Approximately 0.03% of an ophthalmic dose of Sodium Cromoglycate 2% Eye Drops is absorbed systemically. Sodium Cromoglycate 2% Eye Drops prevent, release of mediators of type-I allergic reactions, including histamine and slow reacting substance of anaphylaxis (SRS-A) from sensitised mast cells after the antigen antibody union has taken place. The drug does not inhibit the binding of IgE to mast cells nor the interaction between cell bound IgE and the specific antigen; instead Sodium Cromoglycate suppresses the release of substances (e.g. histamine, SRS-A) in response to this reaction. The drug also inhibits Type-III (late allergic, Arthus) reactions.

Dosage And Administration of Nasochrom Ophthalmic Solution Eye Drop 2%

The usual dosage of Nasochrom Ophthalmic Solution Eye Drop 2% (Sodium Cromoglicate [2%]) Cromoglycate 2% Eye Drops in adults and children over 4 years of age or older is 1 or 2 drops in each eye 4-6 times daily at regular intervals. The recommended frequency of administration should not be exceeded. Patients should be advised that the therapeutic effects of Sodium Cromoglycate 2% Eye Drops depend on administration of the drug at regular intervals.

Drug Interactions of Nasochrom Ophthalmic Solution Eye Drop 2%

Nasochrom Cromoglycate has no known drug interactions.

Side Effects of Nasochrom Ophthalmic Solution Eye Drop 2%

The most frequent adverse effect reported with use of Nasochrom Cromoglycate 2% Eye Drops is transient ocular stinging or burning upon instillation of the drug.

Precautions And Warnings for Nasochrom Ophthalmic Solution Eye Drop 2%

Nasochrom Cromoglycate 2% Eye Drops contains benzalkonium chloride and patients should be advised not to wear soft contact lenses during treatment with Nasochrom Cromoglycate 2% Eye Drops.

Use During Pregnancy and Lactation

In animal studies, Nasochrom Ophthalmic Solution Eye Drop 2% (Sodium Cromoglicate [2%]) Cromoglycate has produced adverse effects on the foetus only in high parenteral doses. There was no evidence of impaired fertility in reproduction studies in animals. Healthy infants have been born to women who received Sodium Cromoglycate throughout pregnancy; nevertheless, there is insufficient evidence to establish the safety in pregnancy. It should be used during pregnancy only when clearly needed. Since it is not known if Sodium Cromoglycate is distributed into milk in humans, the drug should be used with caution in nursing women.

Therapeutic Class

Mast Cell Stabiliser, Ophthalmic Non-Steroid drugs

Storage Conditions of It

Nasochrom Cromoglycate 2% Eye Drops should be protected from direct sunlight and stored at a temperature less than 30˚C; any unused ophthalmic solution should be discarded 4 weeks after opening the cap of the bottle. Thanks for using MedEx! How would you rate your experience so far?