OTC

Miclo 0.0005

General Pharmaceuticals Ltd. · Ointment

GenericClobetasone Butyrate

Strength0.0005

Unit Price

৳ 40

/ 10 gm tube

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Medicine Description

INDICATIONS

Clobetasone Butyrate preparations are indicated for the treatment of eczema and dermatitis of all types including atopic eczema, photodermatitis, otitis externa, primary irritant allergic dermatitis (including napkin rash), intertrigo, prurigo nodularis, seborrhoeic dermatitis and insect bite reactions. Clobetasone Butyrate may be used as a maintenance therapy between courses of one of the more active topical steroids.

PHARMACOLOGY

Clobetasone Butyrate is a topically active corticosteroid, which provides an exceptional combination of activity and safety. It is more effective in the treatment of eczemas than 1% Hydrocortisone, or the less active synthetic steroid preparations that are in common use. It has little effect on hypothalamic-pituitary-adrenal function. All topical corticosteroids can cause cutaneous atrophy if grossly misused. However, study in animal and human models indicates that Clobetasone Butyrate causes less thinning of the epidermis than the other topical steroid tested.

DOSAGE & ADMINISTRATION

Apply to the affected area up to four times a day until improvement occurs, when the frequency of application may be reduced.

INTERACTION

Potentially hazardous interactions- none has been reported. Potentially useful interactions- none has been reported.

SIDE EFFECTS

In the unlikely event of signs of hypersensitivity appearing, application should stop immediately. When large areas of the body are being treated with Clobetasone Butyrate, it is possible that some patients will absorb sufficient steroid to cause transient adrenal suppression despite the low degree of systemic activity associated with Clobetasone Butyrate.Local atopic changes could possibly occur in situations where moisture increases absorption of Clobetasone Butyrate, but only after prolonged use.There are reports of pigmentation changes and hypertrichosis with topical steroids.Exacerbation of symptoms may occur.

PREGNANCY & LACTATION

There is inadequate evidence of safety in human pregnancy. Topical administration of corticosteroids to pregnant animals can cause abnormalities of fetal development including cleft palate and intrauterine growth retardation. There may therefore be a very small risk of such effects in the human fetus.

PRECAUTIONS & WARNINGS

May be absorbed in sufficient amounts to cause systemic effects when applied topically to large areas, broken skin or under occlusive dressings. Peptic ulcer, osteoporosis, psychoses or severe psychoneuroses. Not to be used indiscriminately for pruritus. CHF or hypertension. Diabetes mellitus, epilepsy, glaucoma, infectious diseases, ocular herpes simplex, chronic renal failure and uraemia. Active or doubtfully quiescent tuberculosis. Local treatment of eye disorders. Elderly. Prolonged use on the face.