Lymeclin 408 mg

Lymeclin 408 mg | INDICATIONS AND USES

Lymecycline is indicated for the treatment of acne, ear, nose and throat infections, acute exacerbation of chronic bronchitis, gastro-intestinal infection, urinary tract infection, non-gonococcal urethritis, trachoma, rickettsial fever, soft tissue infection.

Lymeclin 408 mg | PHARMACOLOGY

Lymecycline is is approximately 5000 times more soluble than tetracycline base and is unique amongst tetracyclines in that it is absorbed by an active transport process across the intestinal wall, ensuring greater absorption.Lymecycline is a tetracycline derivative which blocks the access of bacterial aminoacyl-tRNA to the mRNA-ribosome complex by binding to the 30S ribosome subunit, preventing the addition of amino acids to the growing peptide chain in protein synthesis

Lymeclin 408 mg | DOSAGE & ADMINISTRATION

Adults: The usual dosage for the chronic treatment of acne is 1 capsule daily: Treatment should be continued for at least 8 weeks. For other infections, the usual dosage is 1 capsule twice daily. If higher doses are required, 3-4 capsules may be given over 24 hours. Duration should be determined by the physician. Lower doses may be given for prophylaxis.Elderly: As for other tetracyclines, no specific dose adjustment is required.Children: Not recommended for children under the age of 12 years. For children over the age of 12 years the adult dosage may be given.Lymecycline capsule should always be taken with a glass of water.

Lymeclin 408 mg | DRUG INTERACTIONS

The absorption of tetracyclines may be affected by the simultaneous administration of Calcium, Aluminium, Magnesium, Bismuth and Zinc salts, antacids, iron preparations and quinapril. These products should not be taken within two hours before or after taking Lymecycline. Unlike earlier tetracyclines, absorption of Lymecycline is not significantly impaired by moderate amounts of milk. An increase in the effects of anticoagulants may occur with tetracyclines. Concomitant use of diuretics should be avoided.

Lymeclin 408 mg | SIDE EFFECTS

Care should be exercised in administering Lymecycline to patients with hepatic impairment.

Lymeclin 408 mg | USE DURING PREGNANCY AND LACTATION

Lymecycline are selectively absorbed by developing bones and teeth and may cause dental staining and enamel hypoplasia. In addition, these compounds readily cross the placental barrier and therefore Lymecycline should not be given to pregnant or lactating women.

Lymeclin 408 mg | PRECAUTIONS & WARNINGS

Patient with myasthenia gravis. May exacerbate SLE. Hepatic impairment.

Lymeclin 408 mg | THERAPEUTIC CLASS

Tetracycline group of drugs

Lymeclin 408 mg | STORAGE CONDITIONS

Store at temperature not exceeding 30°C in a dry place. Protect from light.