Lyco (1500 mg+250 mg)/5 ml is a Product of the Generic Potassium Citrate + Citric Acid

What Is Lyco (1500 mg+250 mg)/5 ml Indications and Uses?

This preparation oral solution is indicated in the following cases:

To relieve discomfort in urinary tract infections
To prevent kidney stone
With uricosuric agent to prevent gout
Acidosis caused by kidney diseases

Pharmacology (Source, Chemical and Physical Composition) Of Lyco (1500 mg+250 mg)/5 ml

Potassium Citrate is absorbed and metabolized to potassium bicarbonate, this acting as a systemic alkalizer. The effects are essentially those of chlorides before absorption and those of bicarbonates subsequently. Oxidation is virtually complete so that less than 5% of the potassium citrate is excreted in the urine unchanged.

Dosage And Administration of Lyco (1500 mg+250 mg)/5 ml

Oral Solution should be taken diluted in water according to directions, followed by additional water, if desired. Palatability is enhanced if chilled before taking. Proper dilution may help prevent gastrointestinal injury associated with the oral ingestion of concentrated potassium salt preparations.To relieve discomfort in UTI:

Adults and children over 6 years: 10 ml 3 times daily, diluted with 1 glass of water.
Children 1-6 years: 5 ml 3 times daily, diluted with ½ glass of water.

To prevent kidney stones, With a uricosuric agent to prevent gout, Acidosis caused by kidney diseases:

Adults: 10-15 ml 4 times daily (or as directed by the physician) diluted with 1 glass of water.
Pediatric: 5-10 ml 4 times daily (or as directed by the physician) diluted with ½ glass of water.

Drug Interactions of Lyco (1500 mg+250 mg)/5 ml

Concurrent administration of potassium-containing medication, potassium-sparing diuretics, angiotensin-converting enzyme (ACE) inhibitors or cardiac glycosides may lead to toxicity.

Side Effects of Lyco (1500 mg+250 mg)/5 ml

This solution is generally well tolerated without any unpleasant side effect when given in recommended doses to patients with normal renal function and urinary output. However, as with any alkalinizing agent, caution must be used in certain patients with abnormal renal mechanisms to avoid development of hyperkalemia or alkalosis. Potassium intoxication causes listlessness, weakness, mental confusion, tingling of extremities and other symptoms associated with a high concentration of Potassium in the serum.

Use During Pregnancy and Lactation

There are no adequate data from the use of Potassium Citrate oral solution in pregnant women. Animal studies are insufficient with respect to effects on pregnancy. The potential risk to humans is unknown. Potassium Citrate oral solution should not be used during pregnancy unless clearly necessary and on the advice of a physician.

Precautions And Warnings for Lyco (1500 mg+250 mg)/5 ml

The solution should be used with caution in patients with low urinary output. It should be diluted adequately with water to minimize the possibility of gastrointestinal injury associated with the oral ingestion of concentrated Potassium salt preparations; and preferably, to take each dose after meals. Large doses may cause hyperkalemia and alkalosis, especially in the presence of renal disease.Large doses may cause hyperkalemia an alkalosis, especially in the presence of renal disease. Concurrent administration of potassium-containing medication, potassium-sparing diuretics, angiotensin-converting enzyme (ACE) inhibitors, or cardiac glycosides may lead to toxicity. Do not exceed recommended dosage. Discontinue use if adverse reaction occurs.Should be used with caution by patients with low urinary output unless under the supervision of a physician. As with all liquids containing a high concentration of potassium, patients should be directed to dilute adequately with water to minimize the possibility of gastrointestinal injury associated with the oral ingestion of concentrated potassium salt preparations; and preferable, to take each dose after meals to avoid saline laxative effect.

Therapeutic Class

Prevention of repeated kidney stone formation, Urinary Alkalinizing Agent

Storage Conditions of It

Keep below 30°C temperature, away from light & moisture. Keep out of the reach of children.