Kanaquine 300 mg/5 ml is a Product of the Generic Quinine Sulfate

Kanaquine 300 mg/5 ml belongs to the generic category of Quinine Sulfate. This medicine should be used according to a doctor's advice. We have provided detailed information about the uses, dosage, effectiveness, side effects, precautions, drug interactions, storage conditions, and other important details of Kanaquine 300 mg/5 ml. Our goal is to present essential medicine information in one place for patients, caregivers, and healthcare professionals. To better understand Quinine Sulfate and ensure the safe use of this medicine, please read the information below carefully and consult a healthcare professional when necessary.

Description of Kanaquine 300 mg/5 ml

Kanaquine 300 mg/5 ml may be available as a prescription or over-the-counter medicine, depending on local regulations and medical recommendations. It is used for the treatment and management of specific conditions or symptoms. The way this medicine is used may vary depending on the patient's condition and the advice of a healthcare provider. Detailed information about the approved uses, therapeutic applications, and other relevant details of Kanaquine 300 mg/5 ml is provided below to help users gain a clear understanding of this medicine.

What Is Kanaquine 300 mg/5 ml Indications and Uses?

Quinine Sulfate is indicated in-

Uncomplicated, severe and complicated falciparum malaria
Falciparum malaria resistant to other drugs
Prevention of nocturnal muscle cramps
Alleviation of muscle cramps in Thomsen's disease.

Pharmacology (Source, Chemical and Physical Composition) Of Kanaquine 300 mg/5 ml

Quinine is believed to interfere with protein metabolism and inhibits nucleic acid synthesis in malarial parasites. Quinine is a highly active blood schizonticide and suppresses the asexual cycle of development of malaria parasites in the erythrocytes. It is effective both as a suppressive drug and in the over clinical attack of malaria.

Dosage And Administration of Kanaquine 300 mg/5 ml

Adult:

Oral: 600 mg (of quinine salt) every 8 hours for 7 days.
Parenteral: lf the patient is seriously ill quinine should be given by intravenous infusion. The adult dosage regimen for quinine by infusion is loading dose of 20 mg/kg (up to maximum 1.4 g) of quinine salt infused over 4 hours then after 8-12 hours maintenance dose of 10 mg/kg (up to maximum 700 mg) of quinine salt infused over 4 hours every 8-12 hours (until patient can swallow tablets to complete the 7 days course).

Children:

Oral: Quinine is well tolerated by children. The dosage regimen for quinine by mouth for children is 10 mg/kg (of quinine salt) every 8 hours for 7 days.
Parenteral: The dosage regimen for quinine by intravenous infusion for children is calculated on a mg/kg basis as for adult.

Pregnancy: The adult treatment doses of oral and intravenous quinine given above (including the loading dose) can safely be given to pregnant women.

Side Effects of Kanaquine 300 mg/5 ml

Cinchonism which includes tinnitus, headache, nausea and visual disturbances. Hematological disorders and skin reaction may occur.

Use During Pregnancy and Lactation

In pregnancy, the quinine is not necessarily contraindicated. It is considered to be safe when used in therapeutic dosage in pregnancy. It is excreted in breast milk in insignificant amount which does not discard the use in lactation.

Precautions And Warnings for Kanaquine 300 mg/5 ml

Severe heart disease, myasthenia gravis, diabetes mellitus, IV injection should be given slowly. Use of Mefloquine with Quinine sulphate may increase the chance of side effects.

Therapeutic Class

Anti-malarial drugs

Storage Conditions of It

Use of Mefloquine with Quinine sulphate may increase the chance of side effects.

Kanaquine 300 mg/5 ml is a Product of the Generic Quinine Sulfate