OTC

Gatsina 0.003

Ibn Sina Pharmaceuticals Ltd. · Ophthalmic Solution

GenericGatifloxacin

Strength0.003

Unit Price

৳ 100

/ 5 ml drop

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The information provided on All Samadhan is intended for general informational purposes only and is prepared based on our best practices. It is not a substitute for professional medical advice, diagnosis, or treatment. While we strive to keep the information accurate and up to date, we do not guarantee its completeness or accuracy. The absence of specific information or warnings about any medicine or service should not be considered as an assurance or endorsement by All Samadhan. All Samadhan shall not be held responsible for any consequences arising from the use of this information. We strongly recommend consulting a qualified healthcare professional or physician for any medical concerns, questions, or clarifications.

Medicine Description

INDICATIONS

Gatifloxacin eye drops is indicated for the treatment of bacterial conjunctivitis caused by susceptible strains of the following organisms:Aerobic Gram-Positive Bacteria:

Corynebacterium propinquum
Staphylococcus aureus
Staphylococcus epidermidis
Streptococcus mitis
Streptococcus pneumoniae

Aerobic Gram-Negative Bacteria:

Haemophilus influenzae.

PHARMACOLOGY

Gatifloxacin eye drops is an 8-methoxyfluoroquinolone anti-infective for topical ophthalmic use. The antibacterial action of Gatifloxacin results from inhibition of DNA gyrase and topoisomerase IV. DNA gyrase is an essential enzyme that is involved in the replication, transcription and repair of bacterial DNA. Topoisomerase IV is an enzyme known to play a key role in the partitioning of the chromosomal DNA during bacterial cell division. It appears that the C-8-methoxy moiety contributes to enhanced activity and lower selection of resistant mutants of gram-positive bacteria compared to the nonmethoxy C-8 moiety.

DOSAGE & ADMINISTRATION

Gatifloxacin 0.3%: The recommended dosage regimen for the treatment of bacterial conjunctivitis is:

Days 1 and 2: Instill one drop every two hours in the affected eye(s) while awake, up to 8 times daily.
Days 3 through 7: Instill one drop up to 4 times daily while awake.

Gatifloxacin 0.5%: Patients 1 year of age or older:

Day 1: Instill one drop every two hours in the affected eye(s) while awake, up to 8 times.
Days 2 through 7: Instill one drop two to four times daily in the affected eye(s) while awake.

INTERACTION

Specific drug interaction studies have not been conducted with Gatifloxacin eye drops.

SIDE EFFECTS

The most frequently reported adverse events in the overall study population were conjunctival irritation, increased lacrimation etc.

PREGNANCY & LACTATION

Because there are no adequate and well-controlled studies in pregnant women, Gatifloxacin eye drops should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus. It is not known whether this drug is excreted in human milk. Because many drugs are excreted in human milk, caution should be exercised when Gatifloxacin is administered to a nursing woman.

PRECAUTIONS & WARNINGS

Patients should be advised not to wear contact lenses if they have signs and symptoms of bacterial conjunctivitis. Avoid contaminating the applicator tip with material from the eye, fingers or other source.