Fungin-B 0.05%+1%

Fungin-B 0.05%+1% | INDICATIONS AND USES

This topical preparation is indicated for the topical treatment of inflammatory dermal infections like-

Tinea pedis
Tinea cruris
Tinea corporis etc.

Fungin-B 0.05%+1% | PHARMACOLOGY

Clotrimazole is a broad-spectrum antifungal agent used for the treatment of superficial infections caused by species of pathogenic dermatophytes, yeasts and Malassezia furfur. The mechanism of action involves inhibition of the synthesis of ergosterol, a major sterol in the fungal cell membrane. This leads to instability of the cell membrane and eventual death of the fungus. Betamethasone dipropionate is a corticosteroid with anti-inflammatory, antipruritic, and vasoconstrictive properties. But the exact mechanism of action of corticosteroids is not clearly known.

Fungin-B 0.05%+1% | DOSAGE & ADMINISTRATION

Sufficient topical preparation should be applied onto the affected and surrounding skin areas twice a day, in the morning and evening, for 2 weeks in tinea cruris and tinea corporis and for 4 weeks in tinea pedis. The use of this cream for longer than four weeks is not recommended.The safety and effectiveness of the preparation have not been established in children below the age of 12 years.

Fungin-B 0.05%+1% | DRUG INTERACTIONS

No information is available of drug interaction.

Fungin-B 0.05%+1% | SIDE EFFECTS

Adverse reactions reported for the preparation in clinical trials were paresthesia in 1.9% of patients, rash, edema and secondary infection, each in less than 1% of patients. Other adverse reactions reported with the preparation were burning and dry skin in 1.6% of patients and stinging in less than 1% of patients

Fungin-B 0.05%+1% | USE DURING PREGNANCY AND LACTATION

There is inadequate evidence of safety in pregnancy. Clotrimazole has no teratogenic effect in animals but is foetotoxic at high oral doses. Topical administration of corticosteroids to pregnant animals can cause abnormalities of fetal development. Hence the cream should only be used in pregnancy if the benefit justifies the potential risk to the fetus and such use should not be extensive,i.e. in large amounts or for long periods. It is not known whether the components of the preparation are excreted in human milk and therefore caution should be exercised when treating nursing mothers.

Fungin-B 0.05%+1% | THERAPEUTIC CLASS

Betamethasone & Combined preparations

Fungin-B 0.05%+1% | STORAGE CONDITIONS

Keep below 30°C temperature, away from light & moisture. Keep out of the reach of children.