Flutide Metered-Dose Inhaler (MDI) Inhaler (125 mcg+5 mcg)/puff is a Product of the Generic Fluticasone Propionate + Formoterol Fumarate

What Is Flutide Metered-Dose Inhaler (MDI) Inhaler (125 mcg+5 mcg)/puff Indications and Uses?

Asthma : Flutide is a fixed-dose combination of Flutide Metered-Dose Inhaler (MDI) Inhaler (125 mcg+5 mcg)/puff (Fluticasone Propionate + Formoterol Fumarate) and Formoterol Fumarate is indicated in the regular treatment of asthma where the use of a combination product (an inhaled corticosteroid and a long-acting ß2 agonist) is appropriate: For patients not adequately controlled with inhaled corticosteroids and "as required" inhaled short-acting ß2 agonist. Or, ... Read more Asthma : Flutide is a fixed-dose combination of Flutide Metered-Dose Inhaler (MDI) Inhaler (125 mcg+5 mcg)/puff (Fluticasone Propionate + Formoterol Fumarate) and Formoterol Fumarate is indicated in the regular treatment of asthma where the use of a combination product (an inhaled corticosteroid and a long-acting ß2 agonist) is appropriate: For patients not adequately controlled with inhaled corticosteroids and "as required" inhaled short-acting ß2 agonist. Or, For patients already adequately controlled on both an inhaled corticosteroid and a long-acting ß2 agonist. Fluticasone Propionate 125 mcg and Formoterol Fumarate 5 mcg inhaler are indicated in adults and adolescents aged 12 years and above. COPD : Flutide is recommended when a long-acting ß2 agonist/Inhaled corticosteroid is indicated & patients are unable to use other long-acting ß2 agonist/Inhaled corticosteroid. Fluticasone Propionate 125 mcg and Formoterol Fumarate 5 mcg inhaler is indicated in adults only.

Pharmacology (Source, Chemical and Physical Composition) Of Flutide Metered-Dose Inhaler (MDI) Inhaler (125 mcg+5 mcg)/puff

This inhaler (a pressurised inhalation, suspension) which contains two active ingredients: Flutide Metered-Dose Inhaler (MDI) Inhaler (125 mcg+5 mcg)/puff (Fluticasone Propionate + Formoterol Fumarate) which belongs to a group of medicines called steroids. Steroids help to reduce swelling and inflammation in the lungs. Formoterol fumarate dihydrate which belongs to a group of medicines called long-acting beta 2 agonists. Long-acting beta 2 agonists are long-acting bronchodilators which help the airways in your lungs to stay open, making it easier for you to breathe. Together these two active ingredients help to improve your breathing. It is advised that you should use this medicine every day as directed by your doctor or asthma nurse. This medicine helps to prevent breathing problems such as asthma and helps to stop you becoming breathless and wheezy. However, it does not work if you are already having an asthma attack i.e. you are already breathless and wheezing. You will need to use a fast acting ‘reliever’ medicine such as salbutamol if this happens.

Drug Interactions of Flutide Metered-Dose Inhaler (MDI) Inhaler (125 mcg+5 mcg)/puff

No formal drug interaction studies have been performed with this inhaler. Flutide Metered-Dose Inhaler (MDI) Inhaler (125 mcg+5 mcg)/puff (Fluticasone Propionate + Formoterol Fumarate), an individual component of this inhaler, is a substrate of CYP 3A4. The effects of short-term co-administration of strong CYP 3A4 inhibitors (e.g. Ritonavir, Atazanavir, Clarithromycin, Indinavir, Itraconazole, Nelfinavir, Saquinavir, Ketoconazole, Telithromycin) together with this inhaler is of minor clinical relevance, but caution needs to be taken in long-term treatment and co-administration with such drugs should be avoided if possible.

Side Effects of Flutide Metered-Dose Inhaler (MDI) Inhaler (125 mcg+5 mcg)/puff

As with other inhalation therapy, paradoxical bronchospasm may occur with an immediate increase in wheezing and shortness of breath after dosing. Since Flutide inhaler contains both Flutide Metered-Dose Inhaler (MDI) Inhaler (125 mcg+5 mcg)/puff (Fluticasone Propionate + Formoterol Fumarate) and FormoterolFumarate, the same pattern of undesirable effects as reported for these substances may occur. In the unlikely event of a hypersensitivity reaction to Flutide inhaler, treatment should be initiated in accordance with standard treatment for any other hypersensitivity reaction, which may include the use of antihistamines and other treatment as required. Flutide inhaler may need to be discontinued immediately and an alternative asthma therapy may need to be initiated if necessary. Dysphonia and candidiasis may be relieved by gargling or rinsing the mouth with water or brushing the teeth after using the product. Symptomatic candidiasis can be treated with topical anti-fungal therapy whilst continuing the treatment with Flutide inhaler.

Use During Pregnancy and Lactation

Pregnancy : There are limited data on the use of Flutide Metered-Dose Inhaler (MDI) Inhaler (125 mcg+5 mcg)/puff (Fluticasone Propionate + Formoterol Fumarate) and FormoterolFumarate, either administered alone or together but administered from separate inhalers, or on the use of this fixed-dose combination, this inhaler in pregnant women. Studies in animals have shown reproductive toxicity. Administration of this inhaler is not recommended during pregnancy, and should only be considered if expected benefit to the mother is greater than any possible risk to the fetus. If this is the case, then the lowest effective dose needed to maintain adequate asthma control should be used. Breastfeeding : It is not known whether Fluticasone Propionate or FormoterolFumarateare excreted in human breast milk. Therefore, a decision must be made whether to discontinue breastfeeding or to discontinue/abstain from this inhaler therapy taking into account the benefit of breastfeeding for the child and the benefit of therapy for the woman. Fertility : There are no data available on effects on fertility following administration of this inhaler. In animal studies, no effects on fertility have been seen following administration of the individual active substances at clinically relevant doses.

Therapeutic Class

Respiratory corticosteroids

Storage Conditions of It

Store in a cool and dry place, protected from light. Pack Image: Flutide (125 mcg+5 mcg)/puff Inhaler Thanks for using MedEx! How would you rate your experience so far?