Join Our Network
Pharmacy / Merchant
Copyright © All Samadhan - Operated by M/S. Genius Experts | All Rights Reserved
DBID
Registration ID: 176322642
Trade License: TRAD/DNCC/040904/2023
Copyright © All Samadhan - Operated by M/S. Genius Experts | All Rights Reserved
DBID
Registration ID: 176322642
Trade License: TRAD/DNCC/040904/2023
Aristopharma Ltd. · Ophthalmic Solution
/ 5 ml drop
The information provided on All Samadhan is intended for general informational purposes only and is prepared based on our best practices. It is not a substitute for professional medical advice, diagnosis, or treatment. While we strive to keep the information accurate and up to date, we do not guarantee its completeness or accuracy. The absence of specific information or warnings about any medicine or service should not be considered as an assurance or endorsement by All Samadhan. All Samadhan shall not be held responsible for any consequences arising from the use of this information. We strongly recommend consulting a qualified healthcare professional or physician for any medical concerns, questions, or clarifications.
Trifluridine Sterile Eye Drops is indicated for the treatment of primary keratoconjunctivitis and recurrent epithelial keratitis due to herpes simplex virus, type 1 and 2.
Trifluridine is a fluorinated pyrimidine nucleoside analog which interferes with DNA synthesis of herpes simplex virus, type 1 and 2 and vaccinia virus. It stops replication of herpes viral DNA in 3 ways:
Competitive inhibition of viral DNA polymerase,
Incorporation into and termination of the growing viral DNA chain and
Inactivation of the viral DNA polymerase.
Children above 6 years of age & adults: Instill 1 drop every 2 hrs. while awake; maximum 9 drops/day until the corneal ulcer has completely re-epithelialized. After re-epithelialization: Instill 1 drop every 4 hrs. or at least 5 drops/day for 7 days is recommended.If there are no signs of improvement after 7 days of therapy or complete re-epithelialization has not occurred after 14 days of therapy, other forms of therapy should be considered. Continuous administration of Fludin eye drops for periods exceeding 21 days should be avoided because of potential ocular toxicity. Use in children: Safety and effectiveness in pediatric patients below 6 years of age have not been established.Use in elderly patients: No overall clinical differences in safety or effectiveness have been observed between elderly and other adult patients.
Reported side effects are mild, transient burning or stinging sensation upon instillation. Other side effects are superficial punctate keratopathy, epithelial keratopathy, hypersensitivity reaction, stromal edema, irritation, keratitis sicca, hyperemia and increased intraocular pressure.
Pregnancy category C. There are no adequate and well-controlled studies in pregnant women. Trifluridine should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus. Use in lactation: It is unlikely that Trifluridine is excreted in human milk after instillation of Trifluridine eye drops because of the relatively small dosage. The drug should not be prescribed for nursing mothers unless the potential benefits outweigh the potential risks.
Trifluridine should be prescribed only for patients who have a clinical diagnosis of herpetic keratitis.
Ophthalmic Anti-viral Products
Store between 2 to 8°C. Do not use longer than 30 days after first opening. Keep out of the reach of children.