Filazine 100 mg is a Product of the Generic Diethylcarbamazine Citrate

Filazine 100 mg belongs to the generic category of Diethylcarbamazine Citrate. This medicine should be used according to a doctor's advice. We have provided detailed information about the uses, dosage, effectiveness, side effects, precautions, drug interactions, storage conditions, and other important details of Filazine 100 mg. Our goal is to present essential medicine information in one place for patients, caregivers, and healthcare professionals. To better understand Diethylcarbamazine Citrate and ensure the safe use of this medicine, please read the information below carefully and consult a healthcare professional when necessary.

Description of Filazine 100 mg

Filazine 100 mg may be available as a prescription or over-the-counter medicine, depending on local regulations and medical recommendations. It is used for the treatment and management of specific conditions or symptoms. The way this medicine is used may vary depending on the patient's condition and the advice of a healthcare provider. Detailed information about the approved uses, therapeutic applications, and other relevant details of Filazine 100 mg is provided below to help users gain a clear understanding of this medicine.

What Is Filazine 100 mg Indications and Uses?

Diethylcarbamazine is indicated for Filariasis, Lymphatic filariasis, Pulmonary eosinophilia, Loiasis, Toxocariasis.

Pharmacology (Source, Chemical and Physical Composition) Of Filazine 100 mg

The mechanism of action of diethylcarbamazine is thought to involve sensitizing the microfilariae to phagocytosis. One study showed that diethylcarbamazine's activity against Brugia malayi microfilariae is dependent on inducible nitric-oxide synthase and the cyclooxygenase pathway. It confirmed the important role of the arachidonic acid metabolic pathway in diethylcarbamazine's mechanism of action in vivo and showes that in addition to its effects on the 5-lipoxygenase pathway, it targets the cyclooxygenase pathway and COX-1.

Dosage And Administration of Filazine 100 mg

Inital: 1 mg/kg/day, may increase to 6 mg/kg/day over 3 days, then maintain for 3 wk. Prophylaxis of loiasis 300 mg/wk.

Drug Interactions of Filazine 100 mg

There are no known drug interactions and none well documented.

Side Effects of Filazine 100 mg

Fever, headache, vomiting, dizziness, drowsiness, nausea, chills.Potentially Fatal: Severe hypersensitivity reactions may occur especially in the treatment of onchocerciasis where rare Mazzotti reaction characterised by rash, itching, headache, muscle and joint pains, tachycardia, postural hypotension may start within 2 hr of drug administration. Encephalitis and retinal haemorrhage.

Use During Pregnancy and Lactation

Pregnancy Category- X. Studies in animals or humans have demonstrated fetal abnormalities and/or there is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience, and the risks involved in use of the drug in pregnant women clearly outweigh potential benefits.

Precautions And Warnings for Filazine 100 mg

Patients with poor health.Lactation: not known if excreted in breast milk

Therapeutic Class

Other Anti-protozoals

Filazine 100 mg is a Product of the Generic Diethylcarbamazine Citrate

Filazine 100 mg

Hudson Pharmaceuticals Ltd. · Tablet

Diethylcarbamazine Citrate