Erdolin 300 mg is a Product of the Generic Erdosteine

What Is Erdolin 300 mg Indications and Uses?

Erdosteine is a mucolytic drug used in the treatment of acute and chronic respiratory diseases. It also improves the symptoms associated with short episodes of chronic bronchitis.

Pharmacology (Source, Chemical and Physical Composition) Of Erdolin 300 mg

Erdosteine is a prodrug that is metabolised into N-thiodiglycolyl-homocysteine whereby free thiol groups are formed leading to the opening of the disulphide bonds of the bronchial mucoproteins, thus reducing the viscosity of mucus and purulent sputum. It also antagonises the local formation of free radicals and inhibits elastase enzyme activity and bacterial adhesion to epithelial cells.

Dosage And Administration of Erdolin 300 mg

The usual dose of elderly patients and adults above 18 years is 1 capsule twice daily for 10 days. But study shows that in chronic cases Erdosteine can be given up to 12 months or as directed by the physician. Erdosteine capsule may be taken with or without food.

Side Effects of Erdolin 300 mg

Common side effect is epigastric pain. Other side effects include headache, cold, taste alterations, nausea, vomiting, diarrhea, angioedema and other skin allergic reactions.

Use During Pregnancy and Lactation

The use of Erdosteine in pregnant or breast-feeding women is not recommended.

Precautions And Warnings for Erdolin 300 mg

It should be used with caution in mild liver failure. In that case, should not exceed a dose of 300 mg per day.

Use In Special Populations

Renal Impairment: CrCl <25 ml/min: Contraindicated.Hepatic Impairment:

Mild to moderate: Max: 300 mg daily.
Severe: Contraindicated.

Therapeutic Class

Cough expectorants & mucolytics

Storage Conditions of It

Keep in a dry place away from light and heat. Keep out of reach of children