Eluxan 100 mg is a Product of the Generic Eluxadoline

What Is Eluxan 100 mg Indications and Uses?

Eluxadoline is indicated in adults for the treatment of irritable bowel syndrome with diarrhea (IBS-D).

Pharmacology (Source, Chemical and Physical Composition) Of Eluxan 100 mg

Eluxadoline is a mu-opioid receptor agonist, kappa opioid receptor agonist & delta opioid receptor antagonist. Eluxadoline works directly in intestine to reduce peristalsis, also makes the nerves in intestine less sensitive to stimulation.

Dosage And Administration of Eluxan 100 mg

The recommended dose is 75 mg tablet taken orally twice daily with food. Patients who develop severe constipation for more than 4 days have to discontinue the drug. If a dose is missed, patient should take the next dose at the regular time and avoid taking two doses at a time.Pediatric Use: Safety and effectiveness in pediatric patients have not been established.Hepatic Impairment: It is contraindicated in patients with severe hepatic impairment.

Drug Interactions of Eluxan 100 mg

Oral Contraceptive, Cyclosporine, Probenecid, Rosuvastatin.

Side Effects of Eluxan 100 mg

Most common adverse reactions are constipation, nausea and abdominal pain.

Use During Pregnancy and Lactation

Pregnancy: Not established.Lactation: Not established.

Precautions And Warnings for Eluxan 100 mg

Sphincter of Oddi spasm and Pancreatitis.Patients who should be monitored closely-

without a gallbladder
with new or worsening abdominal pain
with nausea and vomiting
with acute biliary pain
with liver or pancreatic enzyme elevation

Therapeutic Class

Carboxylic acids and derivatives, Prokinetic drugs

Storage Conditions of It

Store in a cool & dry place, protect from light. Keep out of the reach of children.