Eluxan 100 mg

Eluxan 100 mg | INDICATIONS AND USES

Eluxadoline is indicated in adults for the treatment of irritable bowel syndrome with diarrhea (IBS-D).

Eluxan 100 mg | PHARMACOLOGY

Eluxadoline is a mu-opioid receptor agonist, kappa opioid receptor agonist & delta opioid receptor antagonist. Eluxadoline works directly in intestine to reduce peristalsis, also makes the nerves in intestine less sensitive to stimulation.

Eluxan 100 mg | DOSAGE & ADMINISTRATION

The recommended dose is 75 mg tablet taken orally twice daily with food. Patients who develop severe constipation for more than 4 days have to discontinue the drug. If a dose is missed, patient should take the next dose at the regular time and avoid taking two doses at a time.Pediatric Use: Safety and effectiveness in pediatric patients have not been established.Hepatic Impairment: It is contraindicated in patients with severe hepatic impairment.

Eluxan 100 mg | DRUG INTERACTIONS

Oral Contraceptive, Cyclosporine, Probenecid, Rosuvastatin.

Eluxan 100 mg | SIDE EFFECTS

Most common adverse reactions are constipation, nausea and abdominal pain.

Eluxan 100 mg | USE DURING PREGNANCY AND LACTATION

Pregnancy: Not established.Lactation: Not established.

Eluxan 100 mg | PRECAUTIONS & WARNINGS

Sphincter of Oddi spasm and Pancreatitis.Patients who should be monitored closely-

without a gallbladder
with new or worsening abdominal pain
with nausea and vomiting
with acute biliary pain
with liver or pancreatic enzyme elevation

Eluxan 100 mg | THERAPEUTIC CLASS

Carboxylic acids and derivatives, Prokinetic drugs

Eluxan 100 mg | STORAGE CONDITIONS

Store in a cool & dry place, protect from light. Keep out of the reach of children.