Desocort 0.0025 is a Product of the Generic Desoximetasone

What Is Desocort 0.0025 Indications and Uses?

Desoximetasone cream is indicated for the relief of the inflammatory and pruritic manifestations of corticosteroid-responsive dermatoses.

Pharmacology (Source, Chemical and Physical Composition) Of Desocort 0.0025

The precise mechanism of the antiinflammatory activity of topical steroids in the treatment of steroid-responsive dermatoses, in general, is uncertain. However, corticosteroids are thought to act by the induction of phospholipase A2 inhibitory proteins, collectively called lipocortins. This is achieved first by the drug binding to the glucocorticoid receptors which then translocates into the nucleus and binds to DNA causing various activations and repressions of genes. It is postulated that these proteins control the biosynthesis of potent mediators of inflammation such as prostaglandins and leukotrienes by inhibiting the release of their common precursor arachidonic acid. Arachidonic acid is released from membrane phospholipids by phospholipase A2.

Dosage And Administration of Desocort 0.0025

Apply a thin film of Desoximetasone Cream to the affected skin areas twice daily. Rub in gently.

Side Effects of Desocort 0.0025

Burning, itching, irritation, dryness, folliculitis, hypertrichosis, acneiform eruptions, hypopigmentation, perioral dermatitis, allergic contact dermatitis, maceration of the skin, skin atrophy, striae and miliaria. Adverse reactions are infrequent with topical Desoximetasone, but may occur frequently with the use of occlusive dressings.

Use During Pregnancy and Lactation

There is no adequate and well-controlled study of Desoximetasone in pregnant women. It should be used during pregnancy only if the potential benefits justifies the potential risks to the fetus. It is not known whether topical administered desoximetasone could result in sufficient systemic absorption to produce detectable quantities in breast milk. Nevertheless, caution should be exercised when topical corticosteroids are administered to a nursing woman.

Precautions And Warnings for Desocort 0.0025

This medication is for external use only. Avoid contact with eyes. The treated skin area should not be bandaged or covered or wrapped unless directed by the physician. Patient should report any sign of local adverse reactions especially under occlusive dressing to the physician.

Therapeutic Class

Other Topical corticosteroids

Storage Conditions of It

Do not store above 30°C. Keep away from light and out of the reach of children.