Delzo Capsule (Enteric Coated) EC Capsule 30 mg is a Product of the Generic Dexlansoprazole

What Is Delzo Capsule (Enteric Coated) EC Capsule 30 mg Indications and Uses?

Healing of Erosive Esophagitis : Delzo is indicated for the healing of all grades of erosive esophagitis (EE) for up to 8 weeks. Maintenance of Healed Erosive Esophagitis : Delzo is indicated to maintain healing of EE and relief of heartburn for up to 6 months. Symptomatic Non-Erosive Gastroesophageal Reflux Disease : Delzo is indicated for the treatment of heartburn associated with symptomatic non-erosive Gastroesophageal Reflux Disease (GERD) for 4 weeks.

Pharmacology (Source, Chemical and Physical Composition) Of Delzo Capsule (Enteric Coated) EC Capsule 30 mg

Delzo Capsule (Enteric Coated) EC Capsule 30 mg (Dexlansoprazole) delayed-release capsule is a Proton Pump Inhibitor (PPI) which suppresses gastric acid secretion by specific inhibition of the (H + /K + )-ATPase in the gastric parietal cell. By acting specifically on the proton pump, Dexlansoprazole blocks the final step of acid production. It is the R-enantiomer of lansoprazole (A racemic mixture of the R- and S-enantiomers). Dexlansoprazole is supplied as a Dual Delayed Release (DDR) formulation in a capsule for oral administration. This capsule contains a mixture of two types of enteric coated granules with different pH-dependent dissolution profiles. The dual delayed release formulation in dexlansoprazole, plasma concentration-time profile with two distinct peaks; the first peak occurs 1 to 2 hours after administration, followed by a second peak within 4 to 5 hours. After oral administration, mean C max and AUC value of Dexlansoprazole increased approximately dose proportionally. Dexlansoprazole is extensively metabolized in the liver and excreated by urine.

Dosage And Administration of Delzo Capsule (Enteric Coated) EC Capsule 30 mg

Delzo Capsule (Enteric Coated) EC Capsule 30 mg (Dexlansoprazole) dosing recommendations- Maintenance of Healed erosive esophagitis and relief of heartburn : 30 mg Once daily Symptomatic Non-Erosive GERD : 30 mg Once daily for 4 weeks Healing of erosive esophagitis : 60 mg Once daily for up to 8 weeks Dexlansoprazole MUPS dosing recommendations- Maintenance of healed erosive esophagitis and relief of heartburn : One 30 mg tablet once daily for 6 months in adults and 16 weeks in patients 12 to 17 years of age Symptomatic Non-Erosive GERD : One 30 mg tablet once daily for 4 weeks. Dexlansoprazole can be taken without regard to food. It should be swallowed whole. Alternatively, Dexlansoprazole capsules can be administered as follows: Open capsule Sprinkle intact granules on one tablespoon Swallow immediately. Granules should not be chewed. If a capsule is missed at its usual time, it should be taken as soon as possible. But if it is too close to the time of the next dose, only the prescribed dose should be taken at the appointed time. A double dose should not be taken.

Drug Interactions of Delzo Capsule (Enteric Coated) EC Capsule 30 mg

With medicine: Atazanavir, Warfarin, Tacrolimus, Clopidogrel & Methotrexate. With food & others: No data available.

Side Effects of Delzo Capsule (Enteric Coated) EC Capsule 30 mg

Common side effects: Diarrhea, abdominal pain, nausea, vomiting & flatulence.

Precautions And Warnings for Delzo Capsule (Enteric Coated) EC Capsule 30 mg

Gastric Malignancy, Clostridium difficile Associated Diarrhea, Bone fracture, Hypomagnesemia, and concomitant use of Delzo with Methotrexate.

Use During Pregnancy and Lactation

Pregnancy Category B. There is no adequate and well-controlled studies with Delzo Capsule (Enteric Coated) EC Capsule 30 mg (Dexlansoprazole) in pregnant women. There is no adequate and well-controlled studies with Dexlansoprazole in Lactating mother.

Therapeutic Class

Proton Pump Inhibitor

Storage Conditions of It

Store below 30°C temperature & in a dry place, protected from light. Keep all medicines out of reach of children. Pack Images: Delzo 30 mg EC Capsule Thanks for using MedEx! How would you rate your experience so far?