Cynovit 1000 mcg/ml is a Product of the Generic Cyanocobalamin

Cynovit 1000 mcg/ml belongs to the generic category of Cyanocobalamin. This medicine should be used according to a doctor's advice. We have provided detailed information about the uses, dosage, effectiveness, side effects, precautions, drug interactions, storage conditions, and other important details of Cynovit 1000 mcg/ml. Our goal is to present essential medicine information in one place for patients, caregivers, and healthcare professionals. To better understand Cyanocobalamin and ensure the safe use of this medicine, please read the information below carefully and consult a healthcare professional when necessary.

Description of Cynovit 1000 mcg/ml

Cynovit 1000 mcg/ml may be available as a prescription or over-the-counter medicine, depending on local regulations and medical recommendations. It is used for the treatment and management of specific conditions or symptoms. The way this medicine is used may vary depending on the patient's condition and the advice of a healthcare provider. Detailed information about the approved uses, therapeutic applications, and other relevant details of Cynovit 1000 mcg/ml is provided below to help users gain a clear understanding of this medicine.

What Is Cynovit 1000 mcg/ml Indications and Uses?

This preparation is indicated in Pernicious anemia, Vitamin B12 deficiency due to low intake from food, Thyrotoxicosis, Hemorrhage, Malignancy, Liver or kidney disease, Gastric bypass surgery, total or partial gastrectomy, Gluten enteropathy or sprue, folic acid deficiency, macrocytic anaemia.

Pharmacology (Source, Chemical and Physical Composition) Of Cynovit 1000 mcg/ml

Vitamin B12 (cyanocobalamin) is required for the maintenance of normal erthropoiesis, nucleprotein and myelin synthesis, cell reproduction and normal growth; Coenzyme; metabolic functions include protein synthesis and carbohydrate metabolism. Plays role in cell replication and hematopoiesis.

Dosage And Administration of Cynovit 1000 mcg/ml

Usual Adult Dose for Pernicious AnemiaInitial dose: 1000 mcg intramuscularly or deep subcutaneous once a day for 6 to 7 daysIf clinical improvement and reticulocyte response is seen from the above dosing:

100 mcg every other day for 7 doses, then
100 mcg every 3 to 4 days for 2 to 3 weeks, then
Maintenance dose: 100 to 1000 mcg monthly

Administer concomitant folic acid if needed. Chronic treatment should be done with an oral preparation in patients with normal intestinal absorption.Usual Adult Dose for B12 Nutritional Deficiency: 25 to 2000 mcg orally dailyUsual Adult Dose for Schilling Test: 1000 mcg intramuscularly is the flushing doseUsual Pediatric Dose for B12 Nutritional Deficiency: 0.5 to 3 mcg daily

Drug Interactions of Cynovit 1000 mcg/ml

Absorption reduced by antibiotics, aminosalicylic acid, anticonvulsants, biguanides, cholestyramine, cimetidine, colchicine, K salts, methyldopa.

Side Effects of Cynovit 1000 mcg/ml

Arthralgia (12%), Dizziness (12%), Headache (12%), Nasopharyngitis (12%), Anaphylaxis, Angioedema, Congestive heart failure, Peripheral vascular disease,Pulmonary edema, Diarrhea, Dyspepsia, Polycythemia vera, Sore throat, Nervousness, Rhinitis, Glossitis, Hypoesthesia

Use During Pregnancy and Lactation

Pregnancy Category A. Adequate and well-controlled human studies have failed to demonstrate a risk to the fetus in the first trimester of pregnancy (and there is no evidence of risk in later trimesters).Lactation: Drug distributed in milk.

Precautions And Warnings for Cynovit 1000 mcg/ml

Intensive treatment of B12-deficient megaloblastic anemia may cause hypokalemia and sudden death. Use with caution in patients with Leber optic nerve atrophy. Thrombocytosis may occur with treatment of severe vitamin B12 megaloblastic anemia

Therapeutic Class

Vitamin-B preparations

Cynovit 1000 mcg/ml is a Product of the Generic Cyanocobalamin