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DBID
Registration ID: 176322642
Trade License: TRAD/DNCC/040904/2023
Copyright © All Samadhan - Operated by M/S. Genius Experts | All Rights Reserved
DBID
Registration ID: 176322642
Trade License: TRAD/DNCC/040904/2023
Sun Pharmaceutical (Bangladesh) Ltd. · Tablet
/ Piece
The information provided on All Samadhan is intended for general informational purposes only and is prepared based on our best practices. It is not a substitute for professional medical advice, diagnosis, or treatment. While we strive to keep the information accurate and up to date, we do not guarantee its completeness or accuracy. The absence of specific information or warnings about any medicine or service should not be considered as an assurance or endorsement by All Samadhan. All Samadhan shall not be held responsible for any consequences arising from the use of this information. We strongly recommend consulting a qualified healthcare professional or physician for any medical concerns, questions, or clarifications.
Clomipramine Hydrochloride is used to treat-
Obsessive Compulsive Disorder (OCD)
Major Depressive Disorder (MDD)
Depression.
Clomipramine Hydrochloride is an original tricyclic antidepressant, a member of the dibenzazepine group of compounds. It is presumed to influence obsessive and compulsive behaviors through it's effects on serotonergic neuronal transmission. The actual neurochemical mechanism is unknown but it has the capacity to inhibit the reuptake of serotonin (5-HT) which is thought to be important (like obsessions, compulsion) thus hampers social acquaintance.
Initial dose is 25 mg at bed time about a week, gradual increase of dose should not be exceeded more than 150 mg per day in adult and 75 mg per day in elderly patient. Dose can be given as divided form to reduce gastrointestinal disturbances. Not recommended for children.
Medicines for depression, particularly-
MAOIs e.g. tranylcypromine, phenelzine, moclobemide;
SSRIs e.g. fluoxetine (or have taken within the last 3 weeks), fluvoxamine, paroxetine, sertraline;
SNaRIs e.g. venlafaxine; tricyclic and tetracyclic antidepressants e.g. amitriptyline, dothiepin, maprotiline
Diuretics, also known as ‘water tablets’, e.g. bendroflumethiazide, furosemide
Anaesthetics, used for the temporary loss of bodily sensation
Blood pressure lowering agents (Beta blockers), Anti-coagulants etc.
The most frequent side effects are gastrointestinal disturbances, Headache, dizziness, nausea, constipation, dry mouth, increased sweating, shaking hands, tremor, difficulty in passing urine, problems with their eyes, feeling tired or sleepy, sexual disturbance, restlessness.
No adequate well-controlled studies of safety for pregnancy. Limited data suggest that clomipramine is likely to be excreted in human breast milk. Although it has known risk of damage to fetus.
Talk to your doctor or pharmacist before taking Clomipramine if you:
have ever had suicidal thoughts
suffer from epilepsy (fits)
have had a head injury or have suffered brain damage
are going to have electric shock therapy (ECT)
have other problems with your heart
have been told you have a low level of potassium in your blood (hypokalaemia). The doctor will need to treat this before you start taking clomipramine
have kidney disease
suffer from schizophrenia or other mental health conditions
have a blood disorder
have an overactive thyroid gland
have had severe constipation for a long time
have a tumour (cancer) of the adrenal gland (such as phaeochromocytoma or neuroblastoma)
liver disease
have low blood pressure
wear contact lenses
Tricyclic & related anti-depressant drugs
Do not store above 30°C. Keep away from light and out of the reach of children.