Cesonide Metered-Dose Inhaler (MDI) Inhaler 80 mcg/actuation is a Product of the Generic Ciclesonide

What Is Cesonide Metered-Dose Inhaler (MDI) Inhaler 80 mcg/actuation Indications and Uses?

Cesonide inhalation aerosol is indicated for treatment to control persistent asthma in adults (18 years and older).

Pharmacology (Source, Chemical and Physical Composition) Of Cesonide Metered-Dose Inhaler (MDI) Inhaler 80 mcg/actuation

Cesonide Metered-Dose Inhaler (MDI) Inhaler 80 mcg/actuation (Ciclesonide), which is a new once daily inhaled corticosteroid, is an ester prodrug that requires hydrolyzation by endogenous esterases in the lung to form its active metabolite (B-9207-021). The activated ciclesonide has an approximately 100-fold greater affinity for glucocorticoid receptors compared with the parent compound and produces high local anti-inflammatory activity.

Drug Interactions of Cesonide Metered-Dose Inhaler (MDI) Inhaler 80 mcg/actuation

Co-administration with a potent inhibitor of the cytochrome P450 3A4 system (e.g. ketoconazole, itraconazole and ritonavir or nelfinavir) should be considered with caution. The risk of clinical adverse effect (eg cushingoid syndrome) cannot be excluded.

Side Effects of Cesonide Metered-Dose Inhaler (MDI) Inhaler 80 mcg/actuation

Common (1-10%): Paradoxical bronchospasm; uncommon (0.1-1%): Bad taste, application site reactions, application site dryness, hoarseness, cough after inhalation, rash and eczema. Systemic effects of inhaled corticosteroids may occur, particularly at high doses prescribed for prolonged periods. These effects are much less likely to occur than with oral corticosteroids. Possible systemic effects include adrenal suppression, growth retardation in children and adolescents, decrease in bone mineral density, cataract and glaucoma. Patients with severe hepatic impairment should be monitored for potential systemic effects.

Precautions And Warnings for Cesonide Metered-Dose Inhaler (MDI) Inhaler 80 mcg/actuation

As with all inhaled corticosteroids, Cesonide should be administered with caution in patients with active or quiescent pulmonary tuberculosis, fungal, viral, or bacterial infections, and only if these patients are adequately treated. As with all inhaled corticosteroids, Cesonide is not indicated in the treatment of status asthmaticus where intensive measures are required, or to relieve acute asthma symptoms for which an inhaled short-acting bronchodilator is required. Patients should be advised to have such rescue medication available. Patients transferred from oral steroids should be monitored regularly and their dose of systemic steroid reduced cautiously. Treatment with Cesonide should not be stopped abruptly.

Use During Pregnancy and Lactation

As with other inhaled glucocorticoids, Cesonide Metered-Dose Inhaler (MDI) Inhaler 80 mcg/actuation (Ciclesonide) should only be used during pregnancy or lactation if the potential benefit to the mother justifies the potential risk to the mother, foetus or child. The lowest effective dose of Ciclesonide needed to maintain adequate asthma control should be used.

Therapeutic Class

Respiratory corticosteroids

Storage Conditions of It

The inhaler should be stored below 30°C, protected from direct sunlight and heat. The canister should not be broken, punctured or burnt, even when apparently empty. Keep away from eyes. Keep out of reach of children. Thanks for using MedEx! How would you rate your experience so far?