Cefida 125 mg/5 ml is a Product of the Generic Cefdinir

What Is Cefida 125 mg/5 ml Indications and Uses?

Cefdinir is indicated in-

Community Acquired Pneumonia,
Acute Exacerbations of Chronic Bronchitis,
Acute Maxillary Sinusitis,
Pharyngitis/Tonsillitis,
Acute Bacterial Otitis Media and
Uncomplicated Skin and Skin Structure Infections.

Pharmacology (Source, Chemical and Physical Composition) Of Cefida 125 mg/5 ml

Cefdinir is a semisynthetic third generation oral cephalosporin antibotic. It has a broad spectrum bactericidal activity against a wide range of common pathogens, including b-lactamase producing strains like Staphylococcus aureus, Streptococcus pneumoniae, Streptococcus pyogenes, Haemophilus influenzae, Moraxella catarrhalis, E. coli, Klebsiella pneumoniae, and Proteus mirabilis. As with other cephalosporins, bactericidal activity of Cefexta results from inhibition of cell wall synthesis.

Dosage And Administration of Cefida 125 mg/5 ml

The total daily dose for all infections is 600 mg. The dosage schedule is given in the following:



Type of infection
Dosage
Duration


Acute Exacerbations of Chronic Bronchitis
300  mg two times daily or 600 mg once daily
5 to 10 days


Pharyngitis/Tonsillitis


Acute Bacterial Otitis Media


Acute Maxillary Sinusitis
300 mg two times daily or 600 mg once daily
10 days


Community Acquired Pneumonia
300mg two times daily
10 days


Uncomplicated Skin and Skin Structure Infections



Powder for Oral Suspension: The total daily dose for all infections is 14 mg/kg body weight up to a maximum dose of 600 mg per day. The dosage schedule of oral suspension for pediatric patients as follows:
 


Type of infection
Dosage
Duration


Acute Bacterial Otitis Media
7mg/kg two times or 14 mg/kg once daily
5 to 10 days


Phayngitis/Tonsilitis
 
 


Acute Maxillary Sinusitis
7mg/kg two times or14 mg/kg once daily
10 days


Uncomplicated Skin and Skin Structure Infections
7mg/kg two times daily
10 days



Direction for Reconstitution of Powder for Suspension: Shake the bottle well so that powder does not clog. Add 40 ml (8 x 5 ml spoonful) boiled and cooled water with the provided 5ml spoon to the bottle. Shake well until all powder is dispersed. Reconstituted suspension should be used within 10 days of preparation if kept at room  temperature or within 14 days if kept in a refrigerator. Shake the bottle well before use.

Drug Interactions of Cefida 125 mg/5 ml

Antacids: Cefdinir should be taken at least 2 hours interval of antacid administration.Iron supplement: Cefdinir should be taken at least 2 hours interval of iron supplement administration.Probencid: It inhibits the renal excretion of cefdinir.

Side Effects of Cefida 125 mg/5 ml

Common side effects are Diarrhea, Vaginal moniliasis, Nausea & Vomiting, Headache, Rash etc.

Use During Pregnancy and Lactation

Its pregnancy category is B. But there are no adequate and well-controlled studies in pregnant women. This drug should be used during pregnancy only if clearly needed. After administration of single 600 mg doses Cefdinir was not detected in the breast milk.

Precautions And Warnings for Cefida 125 mg/5 ml

Cefdinir, as with other broad-spectrum antibiotics, should be prescribed with caution in individuals with a history of colitis. In patients with transient or persistent renal insufficiency (creatinine clearance <30 ml/min), the total daily dose of Cefdinir should be reduced.

Therapeutic Class

Third generation Cephalosporins

Storage Conditions of It

Store at room temperature and protect from light. After reconstitution the suspension can be used within 7 days if kept at room temperature and within 14 days if kept in refrigerator (2-8°C). Always keep the bottle tightly closed.