Cafeta 500 mg+65 mg

Cafeta 500 mg+65 mg | INDICATIONS AND USES

This combination is indicated in the following conditions-

Headache
Migraine
Toothache
Neuralgia
Feverishness
Period pain
Sore throat
Backache
Help to reduce the temperature
Aches and pain of colds and flu

Cafeta 500 mg+65 mg | PHARMACOLOGY

This is a combination of Paracetamol and Caffeine. Paracetamol has analgesic and antipyretic properties with weak anti-inflammatory activity. Caffeine is an alkaloid which is a theophylline-like xanthine derivative. By intermolecular association with Paracetamol, Caffeine increases the solubility and transmembrane permeation of Paracetamol. In addition, Caffeine increases the pain threshold and tolerance of pain. Caffeine has also an intrinsic power to raise vessel tone in the brain, which provides another benefit to treat migraine and headache.

Cafeta 500 mg+65 mg | DOSAGE & ADMINISTRATION

Adult dose: 1-2 tablets every 4-6 hours. Maximum dose: 8 tablets daily. Child dose: Not recommended for children below 12 years.

Cafeta 500 mg+65 mg | DRUG INTERACTIONS

May reduce serum levels with anticonvulsants (e.g. phenytoin, barbiturates, carbamazepine). May enhance the anticoagulant effect of warfarin and other coumarins with prolonged use. Accelerated absorption with metoclopramide and domperidone. May increase serum levels with probenecid. May increase serum levels of chloramphenicol. May reduce absorption with colestyramine within 1 hr of admin. May cause severe hypothermia with phenothiazine.

Cafeta 500 mg+65 mg | SIDE EFFECTS

Side effects of paracetamol are usually mild, though haematological reactions including thrombocytopenia, leukopenia, pancytopenia, neutropenia, and agranulocytosis have been reported. Pancreatitis, skin rashes, and other allergic reactions occur occasionally.

Cafeta 500 mg+65 mg | USE DURING PREGNANCY AND LACTATION

Pregnant mothers should consult with doctors before taking Paracetamol & Caffeine. Paracetamol & Caffeine can be taken whilst breast feeding.

Cafeta 500 mg+65 mg | PRECAUTIONS & WARNINGS

Paracetamol & Caffeine should be given cautiously in the following cases: In patients with hepatic or renal failure, in patients taking other hepatotoxic medication. Prolonged use of the drug without consulting a physician should be avoided.

Cafeta 500 mg+65 mg | THERAPEUTIC CLASS

Non-Opioid Analgesics

Cafeta 500 mg+65 mg | STORAGE CONDITIONS

Store in a cool and dry place, protect from light and moisture.Keep all medicines out of the reach of the children.