Bipinor Plus 5 mg+12.5 mg is a Product of the Generic Nebivolol + Hydrochlorothiazide

Bipinor Plus 5 mg+12.5 mg belongs to the generic category of Nebivolol + Hydrochlorothiazide. This medicine should be used according to a doctor's advice. We have provided detailed information about the uses, dosage, effectiveness, side effects, precautions, drug interactions, storage conditions, and other important details of Bipinor Plus 5 mg+12.5 mg. Our goal is to present essential medicine information in one place for patients, caregivers, and healthcare professionals. To better understand Nebivolol + Hydrochlorothiazide and ensure the safe use of this medicine, please read the information below carefully and consult a healthcare professional when necessary.

Description of Bipinor Plus 5 mg+12.5 mg

Bipinor Plus 5 mg+12.5 mg may be available as a prescription or over-the-counter medicine, depending on local regulations and medical recommendations. It is used for the treatment and management of specific conditions or symptoms. The way this medicine is used may vary depending on the patient's condition and the advice of a healthcare provider. Detailed information about the approved uses, therapeutic applications, and other relevant details of Bipinor Plus 5 mg+12.5 mg is provided below to help users gain a clear understanding of this medicine.

What Is Bipinor Plus 5 mg+12.5 mg Indications and Uses?

This combination is indicated in essential hypertension.

Pharmacology (Source, Chemical and Physical Composition) Of Bipinor Plus 5 mg+12.5 mg

Nebivolol & Hydrochlorothiazide combination has an additive antihypertensive effect, reducing blood pressure to a greater degree than either component alone. This combination has mild vasodilating properties which reduces heart rate and blood pressure in hypertensive patients. Hydrochlorothiazide affects the renal tubular mechanisms of electrolyte reabsorption which directly increase the excretion of sodium and chloride in approximately equivalent amounts. The diuretic action of Hydrochlorothiazide reduces plasma volume, increases plasma renin activity and increases aldosterone secretion.

Dosage And Administration of Bipinor Plus 5 mg+12.5 mg

Once daily, preferably at the same time every day. Use in children is not recommended.

Drug Interactions of Bipinor Plus 5 mg+12.5 mg

Nebivolol:

Class I & III Antiarrhythmics, Calcium channel blocker (Verapamil/Diltiazem)
Centrally-acting antihypertensives, Anaesthetics
Antipsychotics, Antidepressants, NSAIDs

Hydrochlorothiazide:

Drugs affecting Potassium & Calcium level
Non-steroidal anti-inflammatory drugs (NSAIDs)
Concomitant administration of this combination with Antipsychotics, Tricyclic Antidepressants & Barbiturates may enhance the hypotensive effect and lead to postural hypotension.

Side Effects of Bipinor Plus 5 mg+12.5 mg

Nebivolol: Headache, Dizziness, Tiredness, Diarrhoea, Constipation, Nausea etc. Hydrochlorothiazide: Vertigo, Itchiness, Rash, Increased sensitivity of skin to sunlight etc.

Use During Pregnancy and Lactation

This combination is not recommended during pregnancy. It is also not recommended for mothers who are breast-feeding

Precautions And Warnings for Bipinor Plus 5 mg+12.5 mg

Nebivolol: Beta-blockers should not be used in patients with untreated Congestive Heart Failure (CHF) & bradycardia. In patients with Chronic Obstructive Pulmonary Diseases (COPD), beta-blockers should be used with caution as airway constriction may be aggravated.Hydrochlorothiazide: In patients with renal disease, thiazides may increase azotaemia. If progressive renal impairment becomes evident, careful reappraisal of therapy is necessary. Thiazides can cause fluid or electrolyte imbalance. Thiazides may decrease urinary calcium excretion and may cause slight elevation of serum calcium in the absence of known disorders of calcium metabolism

Therapeutic Class

Combined antihypertensive preparations

Storage Conditions of It

Protect from light & moisture. Store below 30°C. Keep out of reach of children.

Bipinor Plus 5 mg+12.5 mg is a Product of the Generic Nebivolol + Hydrochlorothiazide