Atofix 1% w/w
Eskayef Pharmaceuticals Ltd. · Ointment
/ 10 gm tube
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Medicine Description
INDICATIONS
Difamilast ointment is used topically to treat atopic dermatitis, commonly known as eczema.
PHARMACOLOGY
Difamilast is a phosphodiesterase 4 (PDE4) inhibitor. It increases cyclic adenosine 3',5'-monophosphate (cAMP) concentration and consequently suppresses the production of inflammatory cytokines, exerting effects in treatment of atopic dermatitis.
DOSAGE & ADMINISTRATION
The usual adult dosage is an appropriate amount of the Difamilast 1% ointment applied to the affected area twice daily. The usual pediatric dosage is an appropriate amount of the Difamilast 0.3% ointment applied to the affected area twice daily.
SIDE EFFECTS
Well tolerated in recommended dosage. At higher dosage it may cause mild skin reactions at the site of application, such as redness, burning, or stinging.
PREGNANCY & LACTATION
Difamilast is not recommended for pregnant women or women who may possibly be pregnant. For breastfeeding, safety profile has not been fully established.
PRECAUTIONS & WARNINGS
External use only. Difamilast ointment is not for oral, ophthalmic, or intravaginal use.
If there is any hypersensitivity issue with the use of Difamilast, treatment should be discontinued.
STORAGE CONDITIONS
Keep below 30°C temperature, away from light & moisture. Keep out of the reach of children.
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DBID
Registration ID: 176322642
Trade License: TRAD/DNCC/040904/2023
